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Table 2 Associations of circulating heparan sulfate with plasma indices of endothelial injury, coagulation, and inflammation (ProCESS cohort, 6 h after enrollment)

From: Intravenous fluid resuscitation is associated with septic endothelial glycocalyx degradation

Marker Pearson r p-value Number of subjects analyzed
Endothelial Injury/Activation
 sFLT-1 (soluble VEGF-receptor 1) 0.4097 0.0017 56
 Angiopoietin-2 0.2367 0.0790 56
Inflammation
 Tumor necrosis factor-α 0.2325 0.1384 42
 Interleukin-6 0.3537 0.0216 42
Coagulation
 Tissue plasminogen activator 0.3356 0.0114 56
 D-dimer 0.0926 0.5699 40
 Thrombomodulin 0.4997 <0.0001 56
Other
 Lactate -0.0765 0.6527 37