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Table 2 Sensitivity and specificity of somatosensory evoked potentials and other outcome predictors for 6-month neurological outcome

From: Beyond dichotomy: patterns and amplitudes of SSEPs and neurological outcomes after cardiac arrest

 

Good outcome (n = 51)

Poor outcome (n = 141)

Poor outcome prediction

Good outcome prediction

Sensitivity % (95% CI)

Specificity % (95% CI)

Sensitivity % (95% CI)

Specificity % (95% CI)

N20–P25 pattern

 N20 (−), n (%)

0 (0.0)

43 (30.5)

30.5 (23.0–38.8)

100 (93.0–100.0)

  

 P25 (−), n (%)

0 (0.0)

99 (70.2)

70.2 (61.9–77.6)

100 (93.0–100.0)

  

 N20 (−) or P25 (−), n (%)

0 (0.0)

101 (71.6)

71.6 (63.4–78.9).

100.0 (93.0–100.0)

  

N20–P25 amplitude

  < 0.64 μV, n (%)

0 (0.0)

105 (74.5)

74.5 (66.5–81.4)

100 (93.0–100.0)

  

  > 2.31 μV, n (%)

27 (52.9)

5 (3.5)

  

52.9 (38.5–67.1)

96.5 (91.9–98.8)

  > 5.04 μV, n (%)

5 (9.8)

0 (0.0)

  

9.8 (3.3–21.4)

100.0 (97.4–100.0)

Peak level of NSE (n = 160)

(n = 48)

(n = 112)

    

  > 41.7 ng/mL, n (%)

4 (8.3)

91 (81.3)

81.3 (72.8–88.0)

91.7 (80.0–97.7)

  

  > 68.49 ng/mL, n (%)

0 (0.0)

68 (60.7)

60.7 (51.0–69.8)

100 (92.6–100.0)

  

DWI lesion (n = 134)

(n = 36)

(n = 98)

    

 No diffusion-restriction lesion, n (%)

26 (72.2)

5 (5.1)

  

72.2 (54.8–85.8)

94.9 (88.5–98.3)

 No lesion or isolated cortex or deep gray matter lesion, n (%)

34 (94.4)

8 (8.2)

  

94.4 (81.3–99.3)

91.8 (84.6–96.4)

 Multifocal or global lesion, n (%)

2 (5.6)

90 (91.8)

91.8 (84.6–96.4)

94.4 (81.3–99.3)

  
  1. CI confidence interval, NSE neuron-specific enolase, DWI diffusion-weighted imaging