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Table 1 Characteristics of 259 critically ill patients with sepsis or septic shock

From: Mottling score is a strong predictor of 14-day mortality in septic patients whatever vasopressor doses and other tissue perfusion parameters

Demographic data N (%) or Median [IQR]
 Age, year 68 [57–80]
 Male sex 133 (51)
 Body-mass index, kg/m2 25 [22–28]
 SAPS II score, points 54 [41–70]
 SOFA score at day 1, points 10 [5–14]
Pre-existing conditions
 Atherosclerotic disease 67 (26)
 Cirrhosis 27 (12)
Sepsis origin
 Community-acquired pneumonia 113 (44)
 Intra-abdominal 65 (26)
 Urinary tract 28 (11)
 Skin and soft tissue 21 (8)
 Others 27 (11)
Clinical parameters At H0 At H6
 Heart rate, beats/min 105 [89–121] 100 [85–118]
 Mean arterial pressure, mm Hg 71 [63–80] 73 [67–82]
 Cardiac index, l/min/m2 4.9 [3.9–6.2] 5.0 [3.9–6.03]
 Urinary output, ml/kg/h 0.46 [0.13–0.90]
 Arterial lactate, mmol/l 2.8 [1.5–5.6] 2.4 [1.4–5.3]
 Mottling score
  0 109 (42) 125 (49)
  1 22 (8) 36 (14)
  2 51 (20) 29 (11)
  3 41 (16) 29 (11)
  4 16 (6) 14 (5)
  5 20 (8) 24 (9)
Drugs
 Norepinephrine 156 (60) 188 (73)
  Doses, μg/kg/min 0.4 [0.2–0.7] 0.5 [0.2–1]
 Epinephrine 13 (5) 13 (5)
  Doses, μg/kg/min 0.5 [0.2–0.6] 0.6 [0.3–1]
 Dobutamine 3 (1) 4 (2)
  Doses, μg/kg/min 0.4 [0.3–0.75] 0.3 [0.18–1.3]
Mechanical ventilation at day 1 127 (49)
Mortality at day 14 95 (37)
  1. Results are given as N (%) or median [IQR]
  2. Simplified Acute Physiology Score (SAPS II) was calculated within 24 h of intensive care unit admission. Sequential Organ Failure Assessment (SOFA) score was calculated within 24 h of septic shock onset. MAP mean arterial pressure