Table 1 Baseline differences between the included and excluded populations
|  | Included N = 410 | Excluded N = 65 | P value | Deceased < 7 days N = 43 | Discharged < 7 days N = 22 | P value |
|---|---|---|---|---|---|---|
Age, years | 64 ± 15 | 67 ± 12 | 0.06 | 69 ± 11.7 | 64.2 ± 12.8 | 0.13 |
Body mass index | 27.2 ± 5.2 | 27.1 ± 5.7 | 0.94 | 26.9 ± 5 | 27.5 ± 6.4 | 0.69 |
25-Hydroxyvitamin D, ng/ml | 13.2 ± 4.6 | 13.4 ± 5 | 0.67 | 12.9 ± 4.8 | 14.4 ± 5.4 | 0.26 |
1,25-Dihydroxyvitamin D, pg/ml | 42 (38–46) | 47 (36–58) | 0.36 | 29.3 ± 21.5 | 83.1 ± 56.2 | < 0.01 |
Charlson Comorbidity Index | 3 (2.8–3.2) | 3.4 (2.9–3.9) | 0.25 | 3.6 ± 2 | 2.9 ± 1.9 | 0.23 |
SAPS 2 | 32.7 ± 15.4 | 36.6 ± 15 | 0.06 | 39.4 ± 15 | 31 ± 14 | 0.04 |
TISS | 38 ± 7.7 | 37 ± 8.8 | 0.36 | 41.3 ± 7.3 | 28.8 ± 4.6 | < 0.01 |
Male/female gender, N/N | 267/143 | 42/23 | 0.94 | 30/13 | 12/10 | 0.22 |
Chronic kidney disease, N (%) | 113 (27.5) | 21 (32.3) | 0.43 | 18 (41.8) | 3 (13.6) | 0.02 |
Surgical/medical and neuro admission N/N | 240/170 | 14/51 | < 0.01 | 12/31 | 2/20 | 0.08 |
Chronic liver disease, N (%) | 61 (14.9) | 10 (15.4) | 0.85 | 7 (16.3) | 3 (13.6) | 0.78 |
COPD, N (%) | 77 (18.8) | 10 (15.4) | 0.61 | 8 (18.6) | 2 (9.1) | 0.31 |
Ischemic heart disease—chronic heart failure, N (%) | 229 (55.8) | 26 (40) | 0.59 | 26 (60.5) | 8 (36.4) | 0.07 |
Malignant disease, N (%) | 34 (8.3) | 4 (6.2) | 0.55 | 2 (4.7) | 2 (9.1) | 0.48 |
Mechanical ventilation at enrollment, N (%) | 268 (65.0) | 34 (52.0) | 0.09 | 34 (79.1) | 0 | < 0.01 |
Use of vasopressor at enrollment, N (%) | 203 (49.5) | 32 (49.2) | 0.44 | 32 (74.4) | 0 | < 0.01 |