Fig. 5From: Pyroglutamic acidosis by glutathione regeneration blockage in critical patients with septic shockOxide reduced cycle. Glutathione peroxidase-1 (GPX1) is an intracellular antioxidant enzyme that enzymatically reduces hydrogen peroxide to water to limit its harmful effects. GPX glutathione peroxidase, GRd glutathione reductaseBack to article page