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Fig. 1 | Critical Care

Fig. 1

From: Composed endotypes to guide antibiotic discontinuation in sepsis

Fig. 1

Candidate biomarkers to build composed endotypes to guide antibiotic discontinuation. The presence of an interrogation indicates a biomarker with potential to predict uncomplicated outcome but which at the present moment has been tested just at diagnosis or at ICU admission. Those biomarkers with no interrogation have been tested along the course of sepsis. MR-ProADM: mid-regional proadrenomedullin; mHLA-DR: human leukocyte antigen-DR on monocytes; MFI: means of fluorescence intensities; IL7R: interleukin-7 receptor; HPRT: hypoxanthine phosphoribosyltransferase; SRS1: sepsis response signature; GEX: gene expression. Pictograms were taken from “Smart ServierMedical Art” (https://smart.servier.com/)

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