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Table 2 Cumulative burden of abnormal Neurological Pupil index (NPi < 3) is associated with the severity of intracranial hypertension and 6-month Glasgow Outcome Score (GOS)

From: Quantitative pupillometry for the monitoring of intracranial hypertension in patients with severe traumatic brain injury

Intracranial hypertension (ICHT)

No ICHT (N = 22)

Non-refractory ICHT (N = 15)

Refractory ICHT (N = 17)

p value

 % measurements with abnormal NPi < 3

0.5 (0–11)

1 (0–9)

38 (3–96)

0.007*

6-month Glasgow Outcome Score (GOS)**

GOS 4–5 (N = 18)

GOS 1–3 (N = 31)

p value

 % measurements with abnormal NPi < 3

0 (0–7)

15 (1–80)

0.002

  1. Data are presented as median (interquartile range) number of samples with abnormal NPi < 3 during ICP monitoring time
  2. *p value for comparison with refractory ICHT
  3. **Five patients lost to follow-up