An overview of positive cultures and clinical outcomes in septic patients: a sub-analysis of the Prehospital Antibiotics Against Sepsis (PHANTASi) trial

Table 3 The association between a positive (blood) culture and mortality

	p	RR	95% CI
Positive pre-hospital blood culture
	Unadjusted analysis
28-day mortality	0.002	1.82	1.24–2.55
90-day mortality	0.004	1.60	1.16–2.12
	Adjusted analysis^∞
28-day mortality	< 0.001	2.10	1.36–3.09
90-day mortality	0.004	1.71	1.19–2.37
Positive in-hospital blood culture
	Unadjusted analysis
28-day mortality	0.115	1.31	0.92–1.68
90-day mortality	0.059	1.30	0.98–1.68
	Adjusted analysis^∞
28-day mortality	0.025	1.56	1.05–2.25
90-day mortality	0.022	1.45	1.05–1.95
Bacteremia (positive pre-hospital and/or in-hospital blood culture)
	Unadjusted analysis
28-day mortality	0.018	1.42	1.06–1.87
90-day mortality	0.006	1.39	1.09–1.73
90-day mortality	Adjusted analysis^∞
28-day mortality	0.002	1.71	1.22–2.34
90-day mortality	0.002	1.55	1.18–1.99
Culture-positive sepsis (with or without bacteremia)
	Unadjusted analysis
28-day mortality	0.006	1.43	1.11–1.83
90-day mortality	0.001	1.41	1.15–1.71
	Adjusted analysis^∞
28-day mortality	0.004	1.54	1.15–2.03
90-day mortality	< 0.001	1.53	1.21–1.91

^∞Adjusted for age, group allocation, antibiotics at home, hospital location, source of infection, and total amount of blood cultures drawn

ISSN: 1364-8535