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Fig. 1 | Critical Care

Fig. 1

From: Microcirculatory perfusion disturbances following cardiac surgery with cardiopulmonary bypass are associated with in vitro endothelial hyperpermeability and increased angiopoietin-2 levels

Fig. 1

Prolonged postoperative impairment of renal and pulmonary endothelial barrier. Human renal and pulmonary microvascular endothelial cells were exposed to plasma from patients undergoing cardiopulmonary bypass collected before onset of CPB (pre-CPB), after weaning from CPB (post-CPB), and 24 h (+ 24 h) and 72 h (+ 72 h) after surgery. Renal (a) and pulmonary (c) endothelial resistance after plasma exposure over time and quantification of renal (b) and pulmonary (d) endothelial resistance after 3 h. Data represent mean or mean ± SD. One-way ANOVA with Bonferroni post-hoc analysis, *P < 0.05 versus pre-CPB; and repeated measures ANOVA, #P < 0.05. CPB, cardiopulmonary bypass; SD, standard deviation

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Critical Care

ISSN: 1364-8535