Fig. 3
From: Cytokine clearance with CytoSorb® during cardiac surgery: a pilot randomized controlled trial
Coagulation factors measurements throughout the study period. T0, induction of anaesthesia; T2, end of CPB; T3, 6 h after the end of CPB; and T4, 24 h after the end of CPB. AT, antithrombin; F, factor; vWF, von Willebrand factor. The effect of HA on coagulation factors throughout study time points was assessed by repeated measures’ analysis of variance (ANOVA) and analysis of covariance (ANCOVA) models. Final ANCOVA models included FFP administration, fluid balance and baseline value. Statistical threshold was determined as p = 0.016 after Bonferroni correction