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Table 3 Early postresuscitation hemodynamics associated with the time to epinephrine treatment

From: Time to epinephrine treatment is associated with the risk of mortality in children who achieve sustained ROSC after traumatic out-of-hospital cardiac arrest

 

All children with traumatic OHCA and sustained ROSC (n = 222)

HS OHCA (n = 147)

Non-HS OHCA (n = 75)

Time to epinephrine treatment

 

Time to epinephrine treatment

 

Early (n = 48)

Middle (n = 81)

Late (n = 18)

p value

Early (n = 30)

Middle (n = 38)

Late (n = 7)

p value

No. (%)

No. (%)

No. (%)

 

No. (%)

No. (%)

No. (%)

 

Consciousness level (GCS score)a

 > 7

12 (25.0)

17 (21.0)

2 (11.1)

0.018

9 (30.0)

9 (23.7)

1 (14.3)

0.013

 7–4

25 (52.1)

25 (30.9)

5 (27.8)

 

15 (50.0)

11 (28.9)

0 (0)

 

 3

11 (22.9)

39 (48.1)

11 (61.1)

 

6 (20.0)

68 (47.4)

6 (85.7)

 

Cardiac rhythm

 Nonsinus rhythm

15 (31.2)

16 (19.8)

5 (27.8)

0.321

9 (30.0)

11 (28.9)

2 (28.6)

0.994

 Sinus rhythm

33 (68.8)

65 (80.2)

13 (72.2)

 

21 (70.0)

27 (71.1)

5 (71.4)

 

Heart ratea

 Tachycardia

26 (54.2)

44 (54.3)

4 (22.2)

0.014

14 (46.7)

18 (47.4)

2 (28.6)

0.632

 Normal

16 (33.3)

19 (23.5)

5 (27.8)

 

11 (36.7)

11 (28.9)

2 (28.6)

 

 Bradycardia

6 (12.5)

18 (22.2)

9 (50.0)

 

5 (16.6)

9 (23.7)

3 (42.8)

 

Mean blood pressurea

 Hypertension

24 (50.0)

26 (32.1)

3 (16.7)

0.015

14 (46.7)

15 (39.5)

2 (28.6)

0.529

 Normal

16 (33.3)

24 (29.6)

5 (27.8)

 

9 (30.0)

11 (28.9)

1 (14.3)

 

 Hypotension

8 (16.7)

31 (38.3)

10 (55.6)

 

7 (23.3)

12 (31.6)

4 (57.1)

 

Oxygenation

 Hypoxia

11 (22.9)

26 (32.1)

5 (27.8)

0.535

7 (23.3)

11 (28.9)

2 (28.6)

0.867

 Nonhypoxia

37 (77.1)

55 (67.9)

13 (72.2)

 

23 (76.7)

27 (71.1)

5 (71.4)

 

Urine outputa

 < 0.5 mL/kg/h

23 (47.9)

22 (27.2)

11 (61.1)

0.036

8 (26.7)

8 (21.1)

2 (28.6)

0.941

 1–0.5 mL/kg/h

16 (33.3)

39 (48.1)

4 (22.2)

 

12 (40.0)

19 (50.0)

3 (42.8)

 

 > 1 mL/kg/h

9 (18.8)

20 (24.7)

3 (16.7)

 

10 (33.3)

11 (28.9)

2 (28.6)

 

Metabolic acidosis (5)b

 Yes

35 (77.8)

46 (58.2)

15 (83.3)

0.026

16 (53.3)

17 (44.7)

5 (71.4)

0.401

 No

10 (22.2)

33 (41.8)

3 (16.7)

 

14 (46.7)

21 (55.3)

2 (28.6)

 
  1. aSignificant factor
  2. bNumber of patients with missing information
  3. GCS Glasgow Coma Scale