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Table 2 Difference in feed volume, energy and protein delivered between the RBF and VBF groups

From: Safety and efficacy of volume-based feeding in critically ill, mechanically ventilated adults using the ‘Protein & Energy Requirements Fed for Every Critically ill patient every Time’ (PERFECT) protocol: a before-and-after study

Variable

RBF*

VBF*

Change

p

Daily volume (ml): mean (SD)

1093.6 (± 285.3)

1290.7 (± 245.2)

> 197.2ml

0.001

% volume (all): median (IQR)

87.4 (80.5–92.1)

98.2 (95.4–100.0)

> 11.2%

< 0.001

% volume (surgical):

Median (IQR)

82.8 (59.1–88.6) (n = 12)

99.4 (95.1–102.6) (n = 8)

> 16.6%

0.001

Energy (kcal/day)a: mean (SD)

1540.6 (± 380.2)

1784.5 (± 245.1)

> 243.9

< 0.001

% energy (all)a: mean (SD)

87.9 (± 13.8)

101.3 (± 11.7)

> 13.4

< 0.001

% energy (surgical)a:

Median (IQR)

85.3 (67.2–93.4) (n = 12)

100.2 (93.4–112.3) (n = 8)

> 14.9

0.025

Daily kcal/kga,b: mean (SD)

19.9 (± 4.9)

21.7 (± 3.8)

> 1.8

0.052

° BMI < 30 kg/m2

Mean (SD)

n = 33

22.1 (± 3.4)

n = 28

24.5 (± 2.1)

> 2.2

0.004

° BMI ≥ 30 kg/m2

Mean (SD)

n = 13

14.3 (± 3.5)

n = 18

17.6 (± 1.8)

> 3.4

0.006

Protein (g/day): mean (SD)

78.1 (± 19.4)

98.1 (± 23.7)

> 20

< 0.001

% protein (all): mean (SD)

89.2 (± 19.5)

97.6 (± 14.8)

> 8.6

0.022

% protein (surgical):

Median (IQR)

88.3

(63.4–106.1)

108.1

(91.6–116.2)

> 19.8

0.031

Daily g/kgc: mean (SD)

1.2 (± 0.2)

1.4 (± 0.3)

0.2

< 0.001

° BMI < 30 kg/m2c,e

Median (IQR)

n = 32

1.2 (1.1–1.2)

n = 26

1.3 (1.1–1.3)

> 0.1

0.040

° BMI ≥ 30 kg/m2d,e

Median (IQR)

n = 10

1.2 (1.0–1.4);

n = 15

1.8 (1.5–1.9)

> 0.5

0.001

° Surgical

Median (IQR)

n = 12

1.1 (0.8–1.3)

n = 8

1.3 (1.1–1.5)

> 0.2

0.069

° CKD:

Mean (n)

1.0 (4)

1.0 (5)

0

 
  1. p values found using t test for continuous normally distributed outcomes, and Mann Whitney U for continuous non-normally distributed outcomes
  2. n number of, IQR interquartile range, SD standard deviation, BMI body mass index, RBF rate-based feeding, VBF volume-based feeding, ml millilitres, kg kilogrammes, kcal/day kcal per day, g/day grammes per day, kcal/kg kcal per kilogramme, CKD chronic kidney disease
  3. akcal from feed and propofol
  4. bkcal/kg of actual bodyweight
  5. cg/kg of actual bodyweight
  6. dg/kg of ideal bodyweight
  7. eExcluding renal patients
  8. *n = 46 unless otherwise stated