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Fig. 2 | Critical Care

Fig. 2

From: The pharmacokinetic challenge of voriconazole therapy for cerebral aspergillosis in patients treated with ibrutinib

Fig. 2

Time-course of voriconazole and C-reactive protein (CRP) concentrations in the presence and absence of corticosteroids. The X-axis corresponds to time (days). The left Y-axis corresponds to plasma voriconazole concentration (mg/L) and the right Y-axis corresponds to serum CRP levels (mg/L). Plasma voriconazole and CRP concentrations are represented by a black line and a dotted line, respectively. The gray shaded area indicates the therapeutic range of voriconazole (between 1 and 5 mg/L). The lower part of the figure corresponds to the course of serum galactomannan antigen (serum GM) and bronchoalveolar lavage galactomannan antigen (BAL GM). NB: L-Amb: liposomal amphotericin-B

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Critical Care

ISSN: 1364-8535