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Table 1 (abstract P127). Baseline post-cardiotomy coagulation parameters following ECMO initiation by bleeding status

From: 39th International Symposium on Intensive Care and Emergency Medicine

Coagulation Parameter Bleeders (n=30) Non-Bleeders (n=87) P-value
Activated Partial Thromboplastin Time (sec) 150.0 (125.5-150.0) 107.0 (67.0-150.0) 0.006
International Normalized Ratio 2.6 (1.7-3.0) 2.1 (1.6-2.8) 0.419
Activated Clotting Time (sec) 422.0 (248.2-1067.5) 259.0 (160.0-506.0) 0.008
Platelet Count (x109/L) 50.0 (38.7-81.2) 59.0 (40.0-82.0) 0.245
Fibrinogen (mg/dl) 106.5 (74.7-151.2) 139.5 (95.0-181.5) 0.029
Kaolin TEG: R-time, Alpha Angle, Max Amplitude 54.4(28.0-87.3), 13.9(2.6-34.6), 31.1(10.9-40.8) 18.5(11.8-43.6), 29.0(13.7-48.7), 42.4(29.9-52.4) <0.001, 0.002, 0.002
Heparinase TEG: R-time, Alpha Angle, Max Amplitude 11.3(8.4-23.5), 31.9(20.8-43.9), 36.3(22.9-49.1) 9.4(7.2-14.2), 42.5(30.5-54.2), 45.6(37.9-54.9) 0.041, 0.029, 0.016
  1. ECMO = extracorporeal membrane oxygenation, TEG = thromboelastography, R-time = reaction time. Values are median (interquartile range), p-values calculated using the Wilcoxon Rank Sum test. Median baseline labs values are shown, comparable findings were noted when evaluating labs at 4- and 8-hours, and when evaluating maximum and minimum values for patients within the initial 12 ECMO hours. No significant findings for TEG Lysis times