39th International Symposium on Intensive Care and Emergency Medicine

Table 1 (abstract P127). Baseline post-cardiotomy coagulation parameters following ECMO initiation by bleeding status

Coagulation Parameter	Bleeders (n=30)	Non-Bleeders (n=87)	P-value
Activated Partial Thromboplastin Time (sec)	150.0 (125.5-150.0)	107.0 (67.0-150.0)	0.006
International Normalized Ratio	2.6 (1.7-3.0)	2.1 (1.6-2.8)	0.419
Activated Clotting Time (sec)	422.0 (248.2-1067.5)	259.0 (160.0-506.0)	0.008
Platelet Count (x109/L)	50.0 (38.7-81.2)	59.0 (40.0-82.0)	0.245
Fibrinogen (mg/dl)	106.5 (74.7-151.2)	139.5 (95.0-181.5)	0.029
Kaolin TEG: R-time, Alpha Angle, Max Amplitude	54.4(28.0-87.3), 13.9(2.6-34.6), 31.1(10.9-40.8)	18.5(11.8-43.6), 29.0(13.7-48.7), 42.4(29.9-52.4)	<0.001, 0.002, 0.002
Heparinase TEG: R-time, Alpha Angle, Max Amplitude	11.3(8.4-23.5), 31.9(20.8-43.9), 36.3(22.9-49.1)	9.4(7.2-14.2), 42.5(30.5-54.2), 45.6(37.9-54.9)	0.041, 0.029, 0.016

ECMO = extracorporeal membrane oxygenation, TEG = thromboelastography, R-time = reaction time. Values are median (interquartile range), p-values calculated using the Wilcoxon Rank Sum test. Median baseline labs values are shown, comparable findings were noted when evaluating labs at 4- and 8-hours, and when evaluating maximum and minimum values for patients within the initial 12 ECMO hours. No significant findings for TEG Lysis times

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