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Table 2 Baseline characteristics for sepsis patients, stratified by the presence of autoimmune disease

From: The association between autoimmune disease and 30-day mortality among sepsis ICU patients: a cohort study

  Autoimmune disease No autoimmune disease P value
Number of patients 496 5704  
Patient outcomes
 30-day mortality 26.61% 34.55% < 0.001
Patient characteristics
 Age (mean ± SD) 64.46 ± 14.64 66.21 ± 16.48 0.012
 Sex (% male) 44.56% 57.50% < 0.001
 Race    0.027
  White, non-Hispanic 80.04% 71.49%  
  Black, non-Hispanic 7.26% 9.34%  
  Hispanic 2.02% 3.30%  
  Asian/Pacific Islander 1.61% 3.00%  
  Other 2.42% 2.58%  
  Unknown 6.65% 10.29%  
 SOFA at admission (mean ± SD) 5.63 ± 3.67 6.50 ± 3.80 < 0.001
 Elixhauser comorbidity index (mean ± SD) 9.46 ± 7.74 9.75 ± 7.83 0.411
 Infection site (% pulmonary) 32.06% 39.00% 0.003
 Documented bacteremia (% yes) 16.13% 18.92% 0.142
 Chronic pre-admission DMARD or prednisone use 56.05% 19.78% < 0.001
  Chronic prednisone use 41.73% 17.36%  
  Chronic DMARD use 34.48% 5.80%  
 ICU care unit    0.694
  MICU 63.91% 62.34%  
  SICU 21.57% 21.27%  
  CCU 9.88% 10.64%  
  CSRU 4.64% 5.75%  
  1. SOFA Sequential Organ Failure Assessment, DMARD disease-modifying antirheumatic drug, ICU intensive care unit, CCU coronary care unit, CSRU cardiac surgery recovery unit, MICU medical intensive care unit, SICU surgical intensive care unit