Variables | Permissive | Restrictive | Total |
---|---|---|---|
N = 38 | N = 49 | N = 87 | |
Age (years) | |||
Mean (SD) | 1.8 (3.4) | 1.1 (2.1) | 1.4 (2.7) |
Age group (years), n (%) | |||
< 1 | 24 (63.2) | 32 (65.3) | 56 (64.4) |
1 | 3 (7.9) | 4 (8.2) | 7 (8.0) |
2–4 | 5 (13.2) | 9 (18.4) | 14 (16.1) |
5–9 | 3 (7.9) | 3 (6.1) | 6 (6.9) |
10–15 | 3 (7.9) | 1 (2.0) | 4 (4.6) |
Gender, n (%) | |||
Female | 14 (36.8) | 22 (44.9) | 36 (41.4) |
PIM2r scorea | |||
Mean (SD) | 0.025 (0.030) | 0.025 (0.030) | 0.025 (0.029) |
Median (IQR) | 0.012 (0.008,0.035) | 0.012 (0.008,0.037) | 0.012 (0.008,0.036) |
PIM3 score | |||
Mean (SD) | 0.023 (0.033) | 0.025 (0.036) | 0.024 (0.034) |
Median (IQR) | 0.007 (0.005,0.033) | 0.007 (0.005,0.038) | 0.007 (0.005,0.037) |
Source of admission, n (%) | |||
Same hospital | 6 (15.8) | 13 (26.5) | 19 (21.8) |
Other hospital | 32 (84.2) | 36 (73.5) | 68 (78.2) |
Primary diagnosis, n (%) | |||
Bronchiolitis | 19 (50.0) | 24 (49.0) | 43 (49.4) |
Pneumonia/LRTI | 9 (23.7) | 8 (16.3) | 17 (19.5) |
Acute respiratory failure | 4 (10.5) | 7 (14.3) | 11 (12.6) |
Sepsis/septic shock | 2 (5.3) | 6 (12.2) | 8 (9.2) |
Asthma | 2 (5.3) | 1 (2.0) | 3 (3.4) |
Seizures/convulsions | 1 (2.6) | 2 (4.1) | 3 (3.4) |
Other | 1 (2.6) | 1 (2.0) | 2 (2.3) |
Temperature prior to randomization (°C) | |||
Mean (SD) | 38.1 (0.6) | 38.1 (0.7) | 38.1 (0.6) |
Median (IQR) | 38.0 (37.7,38.6) | 37.9 (37.6,38.3) | 37.9 (37.7,38.5) |
Type of ventilation, n (%) | |||
High-flow humidified O2, n (%) | 0 (0) | 2 (4.1) | 2 (2.3) |
Non-invasive, n (%) | 3 (7.9) | 3 (6.1) | 6 (6.9) |
Invasive n (%) | 35 (92.1) | 44 (89.8) | 79 (90.8) |