Age (years)
|
Mean (SD)
|
1.8 (3.4)
|
1.1 (2.1)
|
1.4 (2.7)
|
Age group (years), n (%)
|
< 1
|
24 (63.2)
|
32 (65.3)
|
56 (64.4)
|
1
|
3 (7.9)
|
4 (8.2)
|
7 (8.0)
|
2–4
|
5 (13.2)
|
9 (18.4)
|
14 (16.1)
|
5–9
|
3 (7.9)
|
3 (6.1)
|
6 (6.9)
|
10–15
|
3 (7.9)
|
1 (2.0)
|
4 (4.6)
|
Gender, n (%)
|
Female
|
14 (36.8)
|
22 (44.9)
|
36 (41.4)
|
PIM2r scorea
|
Mean (SD)
|
0.025 (0.030)
|
0.025 (0.030)
|
0.025 (0.029)
|
Median (IQR)
|
0.012 (0.008,0.035)
|
0.012 (0.008,0.037)
|
0.012 (0.008,0.036)
|
PIM3 score
|
Mean (SD)
|
0.023 (0.033)
|
0.025 (0.036)
|
0.024 (0.034)
|
Median (IQR)
|
0.007 (0.005,0.033)
|
0.007 (0.005,0.038)
|
0.007 (0.005,0.037)
|
Source of admission, n (%)
|
Same hospital
|
6 (15.8)
|
13 (26.5)
|
19 (21.8)
|
Other hospital
|
32 (84.2)
|
36 (73.5)
|
68 (78.2)
|
Primary diagnosis, n (%)
|
Bronchiolitis
|
19 (50.0)
|
24 (49.0)
|
43 (49.4)
|
Pneumonia/LRTI
|
9 (23.7)
|
8 (16.3)
|
17 (19.5)
|
Acute respiratory failure
|
4 (10.5)
|
7 (14.3)
|
11 (12.6)
|
Sepsis/septic shock
|
2 (5.3)
|
6 (12.2)
|
8 (9.2)
|
Asthma
|
2 (5.3)
|
1 (2.0)
|
3 (3.4)
|
Seizures/convulsions
|
1 (2.6)
|
2 (4.1)
|
3 (3.4)
|
Other
|
1 (2.6)
|
1 (2.0)
|
2 (2.3)
|
Temperature prior to randomization (°C)
|
Mean (SD)
|
38.1 (0.6)
|
38.1 (0.7)
|
38.1 (0.6)
|
Median (IQR)
|
38.0 (37.7,38.6)
|
37.9 (37.6,38.3)
|
37.9 (37.7,38.5)
|
Type of ventilation, n (%)
|
High-flow humidified O2, n (%)
|
0 (0)
|
2 (4.1)
|
2 (2.3)
|
Non-invasive, n (%)
|
3 (7.9)
|
3 (6.1)
|
6 (6.9)
|
Invasive n (%)
|
35 (92.1)
|
44 (89.8)
|
79 (90.8)
|