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Table 1 Characteristics of included patients, according to the cooling method. Data are expressed as count (%) or median (25th–75th percentiles)

From: Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial

 

IC (n = 218)

SFC (n = 134)

Demographic characteristics

 Age, years

61 [53–53]

63.5 [55–70]

 Male gender, n (%)

189 (87%)

104 (78%)*

 Weight, kg

85 [75–95]

80 [75–90]*

 Previous neurologic disability, n (%)

6 (3%)

4 (3%)

Medical history

 Previous myocardial infarction, n (%)

30 (14%)

24 (18%)

 Previous PCI or CABG, n (%)

27 (12%)

28 (21%)

 Previous cardiac arrest, n (%)

1 (0%)

2 (1%)

 Chronic heart failure, n (%)

9 (4%)

9 (7%)

 Chronic obstructive pulmonary disease, n (%)

13 (6%)

11 (8%)

 Liver cirrhosis, n (%)

2 (1%)

1 (1%)

 Chronic renal failure with dialysis, n (%)

2 (1%)

0 (0%)

 Diabetes mellitus, n (%)

39 (18%)

24 (18%)

 Immunocompromised, n (%)

3 (1%)

0 (0%)

 Previous stroke, n (%)

13 (6%)

13 (10%)

Arrest characteristics

 Home location, n (%)

107 (49%)

85 (63%)*

 Witnessed, n (%)

199 (91%)

124 (93%)

 Bystander initiated CPR, n (%)

178 (82%)

115 (86%)

 Shockable rhythm, n (%)

196 (90%)

116 (87%)

 Time to return of spontaneous circulation, min

21 [15–30]

20 [16–26.8]

 Mechanical chest compression, n (%)

56 (26%)

34 (25%)

 Adrenaline, n (%)

135 (62%)

86 (64%)

 Amiodarone, n (%)

93 (43%)

52 (39%)

 Pre-ICU orotracheal intubation, n (%)

206 (94%)

137 (97%)

 Pre-ICU cooling, n (%)

88 (40%)

59 (44%)

 Coronary angiography, n (%)

184 (84%)

107 (80%)

 PCI, n (%)

84 (39%)

61 (46%)

Characteristics on ICU admission

 Sedation, n (%)

216 (99%)

133 (99%)

 Mean arterial pressure, mmHg

82 [69–96]

73.5 [63.3–84]

 Lactate, mEq/L

2.8 [1.6–4.9]

2.5 [1.3–4.7]

  1. IC intravascular catheter, SFC surface cooling, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, ICU intensive care unit, CPR cardiopulmonary resuscitation. $p < 0.001; *p < 0.05; p < 0.1