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Table 1 Characteristics of included patients, according to the cooling method. Data are expressed as count (%) or median (25th–75th percentiles)

From: Intravascular versus surface cooling for targeted temperature management after out-of-hospital cardiac arrest: an analysis of the TTH48 trial

  IC (n = 218) SFC (n = 134)
Demographic characteristics
 Age, years 61 [53–53] 63.5 [55–70]
 Male gender, n (%) 189 (87%) 104 (78%)*
 Weight, kg 85 [75–95] 80 [75–90]*
 Previous neurologic disability, n (%) 6 (3%) 4 (3%)
Medical history
 Previous myocardial infarction, n (%) 30 (14%) 24 (18%)
 Previous PCI or CABG, n (%) 27 (12%) 28 (21%)
 Previous cardiac arrest, n (%) 1 (0%) 2 (1%)
 Chronic heart failure, n (%) 9 (4%) 9 (7%)
 Chronic obstructive pulmonary disease, n (%) 13 (6%) 11 (8%)
 Liver cirrhosis, n (%) 2 (1%) 1 (1%)
 Chronic renal failure with dialysis, n (%) 2 (1%) 0 (0%)
 Diabetes mellitus, n (%) 39 (18%) 24 (18%)
 Immunocompromised, n (%) 3 (1%) 0 (0%)
 Previous stroke, n (%) 13 (6%) 13 (10%)
Arrest characteristics
 Home location, n (%) 107 (49%) 85 (63%)*
 Witnessed, n (%) 199 (91%) 124 (93%)
 Bystander initiated CPR, n (%) 178 (82%) 115 (86%)
 Shockable rhythm, n (%) 196 (90%) 116 (87%)
 Time to return of spontaneous circulation, min 21 [15–30] 20 [16–26.8]
 Mechanical chest compression, n (%) 56 (26%) 34 (25%)
 Adrenaline, n (%) 135 (62%) 86 (64%)
 Amiodarone, n (%) 93 (43%) 52 (39%)
 Pre-ICU orotracheal intubation, n (%) 206 (94%) 137 (97%)
 Pre-ICU cooling, n (%) 88 (40%) 59 (44%)
 Coronary angiography, n (%) 184 (84%) 107 (80%)
 PCI, n (%) 84 (39%) 61 (46%)
Characteristics on ICU admission
 Sedation, n (%) 216 (99%) 133 (99%)
 Mean arterial pressure, mmHg 82 [69–96] 73.5 [63.3–84]
 Lactate, mEq/L 2.8 [1.6–4.9] 2.5 [1.3–4.7]
  1. IC intravascular catheter, SFC surface cooling, PCI percutaneous coronary intervention, CABG coronary artery bypass graft, ICU intensive care unit, CPR cardiopulmonary resuscitation. $p < 0.001; *p < 0.05; p < 0.1