Table 1 Patients’ characteristics
Adequate sedation level (n = 1710) | Inadequate sedation level (n = 4009) | p | |
|---|---|---|---|
Male sex, N (%) | 946 (55.3) | 2332 (58.2) | 0.05 |
Age, median (IQR), years | 61.4 (45.6–74.3) | 60.6 (43.0–73.8) | 0.08 |
Type of admission, N (%) | 0.05 | ||
Medical | 1280 (74.9) | 3046 (76.0) | |
Elective surgery | 132 (7.7) | 239 (6.0) | |
Urgent surgery | 298 (17.4) | 724 (18.1) | |
Reason for ICU admission, N (%) | < 0.01 | ||
Acute respiratory failure | 466 (27.3) | 857 (21.4) | |
Sepsis | 293 (17.1) | 770 (19.2) | |
Neurological disorders | 204 (11.9) | 612 (15.3) | |
Cardiovascular disorders | 74 (4.3) | 163 (4.1) | |
Comorbidities, N (%) | |||
Cancer | 139 (8.1) | 305 (7.6) | 0.50 |
Heart failure | 97 (5.7) | 245 (6.1) | 0.52 |
Cirrhosis | 35 (2.0) | 118 (2.9) | 0.05 |
AIDS | 73 (4.3) | 192 (4.8) | 0.39 |
Study phase, N (%) | 0.33 | ||
Observational | 861 (50.4) | 2075 (51.8) | |
Interventional | 849 (49.6) | 1934 (49.2) | |
SAPS 3, median (IQR) | 60 (48–71) | 63 (51–75) | < 0.01 |
SOFA, median (IQR) | 6 (3–8) | 7 (4–9) | < 0.01 |
Outcomes | |||
ICU mortality, N (%) | 635 (37.1) | 1948 (48.6) | < 0.01 |
ICU length of stay median (IQR) | 11 (6–18) | 12 (7–19) | < 0.01 |
Hospital mortality, N (%) | 784 (45.8) | 2284 (57.0) | < 0.01 |
Hospital length of stay median (IQR) | 25 (13–45) | 23 (12–43) | < 0.01 |