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Table 1 Patients’ characteristics

From: Organizational factors associated with target sedation on the first 48 h of mechanical ventilation: an analysis of checklist-ICU database

  Adequate sedation level (n = 1710) Inadequate sedation level (n = 4009) p
Male sex, N (%) 946 (55.3) 2332 (58.2) 0.05
Age, median (IQR), years 61.4 (45.6–74.3) 60.6 (43.0–73.8) 0.08
Type of admission, N (%)    0.05
 Medical 1280 (74.9) 3046 (76.0)  
 Elective surgery 132 (7.7) 239 (6.0)  
 Urgent surgery 298 (17.4) 724 (18.1)  
Reason for ICU admission, N (%)    < 0.01
 Acute respiratory failure 466 (27.3) 857 (21.4)  
 Sepsis 293 (17.1) 770 (19.2)  
 Neurological disorders 204 (11.9) 612 (15.3)  
 Cardiovascular disorders 74 (4.3) 163 (4.1)  
Comorbidities, N (%)
 Cancer 139 (8.1) 305 (7.6) 0.50
 Heart failure 97 (5.7) 245 (6.1) 0.52
 Cirrhosis 35 (2.0) 118 (2.9) 0.05
 AIDS 73 (4.3) 192 (4.8) 0.39
Study phase, N (%)    0.33
 Observational 861 (50.4) 2075 (51.8)  
 Interventional 849 (49.6) 1934 (49.2)  
SAPS 3, median (IQR) 60 (48–71) 63 (51–75) < 0.01
SOFA, median (IQR) 6 (3–8) 7 (4–9) < 0.01
Outcomes
 ICU mortality, N (%) 635 (37.1) 1948 (48.6) < 0.01
 ICU length of stay median (IQR) 11 (6–18) 12 (7–19) < 0.01
 Hospital mortality, N (%) 784 (45.8) 2284 (57.0) < 0.01
 Hospital length of stay median (IQR) 25 (13–45) 23 (12–43) < 0.01
  1. AIDS acute acquired immunodeficiency syndrome, ICU intensive care unit, SAPS Simplified Acute Physiology Score, SOFA Sequential Organ Failure Assessment