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Table 1 CSF and serum data

From: Cerebrospinal fluid procalcitonin predicts Gram-negative bacterial meningitis in patients with empiric antibiotic pretreatment

  Total (n = 59) Gram-positive (n = 33) Gram-negative (n = 26) P value
CSF
 PCT, ng/mL 0.2 (0.1–0.5) 0.1 (0.1–0.3) 0.5 (0.2–1.6) < 0.001
 Leukocyte, cells/mm3 230.0 (99.0–1790.0) 214.0 (105.5–1970.0) 237.5 (56.0–1870.0) 0.54
 Neutrophils, cells/mm3 154.1 (13.2–1432.0) 147.6 (7.0–1726.5) 165.0 (23.0–1768.9) 0.91
 Lymphocyte, cells/mm3 50.4 (20.1–114.7) 52.1 (17.4–150.6) 44.3 (23.3–100.5) 0.71
 Protein, g/L 1.6 (0.7–2.9) 1.6 (0.8–2.9) 1.6 (0.7–3.0) 0.95
 Glucose, mg/dL 53.3 (37.3–72.0) 54.0 (38.9–74.7) 48.9 (34.7–69.4) 0.29
 CRP, mg/L 0.3 (0.2–0.9) 0.3 (0.2–1.0) 0.3 (0.2–0.8) 0.82
 First pressure, cmH2O 157.5 (130.0–230.0) 150.0 (127.5–205.0) 180.0 (142.5–285.0) 0.12
 Last pressure, cmH2O 95.0 (70.0–130.0) 90.0 (70.0–128.8) 100.0 (72.5–167.5) 0.26
Serum
 PCT, ng/mL 0.6 (0.1–3.1) 0.4 (0.1–4.3) 0.8 (0.1–2.7) 0.61
 Leukocyte, cells/mm3 11.8 (7.8–14.9) 10.5 (7.0–14.6) 13.2 (9.4–15.0) 0.16
 Glucose, mg/dL 144.5 (120.6–173.8) 142.2 (117.9–175.1) 147.6 (128.5–169.7) 0.34
 CRP, mg/L 9.9 (2.2–59.3) 9.5 (2.0–52.9) 14.6 (2.3–68.0) 0.71
 Albumin, g/L 33.9 ± 4.4 33.1 ± 4.7 34.9 ± 4.0 0.13
CSF/serum ratio
 CSF/serum PCT ratio 0.7 (0.2–1.4) 0.7 (0.2–1.4) 0.7 (0.1–1.4) 0.75
 CSF/serum glucose ratio 0.4 (0.3–0.5) 0.4 (0.3–0.5) 0.3 (0.2–0.4) 0.08
  1. The CSF and serum samples were collected on the same day. Continuous variables were expressed as mean ± standard deviation (normally distributed), as medians and interquartile ranges (IQR, not normally distributed), which were compared using the Student t test or Mann-Whitney U test. The CSF and serum samples were collected on the same day
  2. CSF cerebrospinal fluid, PCT procalcitonin, CRP C-reactive protein