Fig. 2From: Safety and efficacy of regional citrate anticoagulation for continuous renal replacement therapy in liver failure patients: a systematic review and meta-analysisThe pooled rates (95% CI) of filter clotting (a) and citrate accumulation (b), and the pooled MDs of totCa/ionCa ratio (c) and serum citrate level (d) between the start of CRRT and the end of observation. CI, confidence interval; ionCa, ionized calcium; MD, mean difference; M, mild liver failure group; S, Severe liver failure group; totCa, total calciumBack to article page