Table 3 Comparisons of the covariates after propensity score matching
Variables | No diuretic use (n = 1463) | Diuretic use (n = 1463) | P |
|---|---|---|---|
Age (years) | 70.3 ± 11.9 | 69.9 ± 12.3 | 0.472 |
Weight (kg) | 84.4 ± 23.1 | 84.9 ± 24.0 | 0.599 |
Diabetes mellitus, n (%) | 514 (35.2) | 535 (36.5) | 0.418 |
Hypertension, n (%) | 820 (53.5) | 802 (54.8) | 0.503 |
Cardiac disease, n (%) | 829 (58.5) | 842 (57.5) | 0.627 |
AKI, n (%) | 496 (34.1) | 504 (34.4) | 0.755 |
SOFA score on ICU admission, median (IQR) | 6 (4–8) | 6 (4–9) | 0.999 |
Maximum white blood cell count (109/l) | 17.0 ± 7.6 | 17.5 ± 9.9 | 0.198 |
Fluid intake (ml/kg/48 h) | 94.1 ± 57.4 | 95.6 ± 55.7 | 0.483 |
Norepinephrine (mg/kg/48 h) | 0.053 ± 0.139 | 0.052 ± 0.151 | 0.814 |
Dopamine (mg/kg/48 h) | 0.782 ± 3.054 | 0.843 ± 3.665 | 0.623 |
Dobutamine (mg/kg/48 h) | 0.193 ± 1.118 | 0.238 ± 1.789 | 0.411 |
Epinephrine (mg/kg/48 h) | 0.008 ± 0.125 | 0.009 ± 0.084 | 0.676 |
Vasopressin (mg/kg/48 h) | 0.071 ± 0.353 | 0.080 ± 0.359 | 0.495 |
Mechanical ventilation | 1317 | 1317 | 1.000 |
Clinical outcomes | |||
Hospital mortality, n (%) | 231 (15.6) | 165 (11.2) | < 0.001 |
Urine output (ml/kg/48 h) | 44.5 ± 28.6 | 51.3 ± 28.5 | < 0.001 |
Fluid balance (ml/kg/48 h) | 35.3 ± 53.8 | 24.3 ± 58.1 | < 0.001 |
Mean MAP (mmHg) | 74.5 ± 7.8 | 73.0 ± 7.1 | < 0.001 |