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Table 3 Transcranial color-coded duplex sonography variables measured in middle cerebral arteries bilaterally

From: Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury

n = 11

A

Baseline

C

Moderate hyperventilation

D

50 min of moderate hyperventilation

E

Return to baseline

CBFV right (cm/s)

81 (23)

69 (21)*

71 (20)*

77 (28)

CBFV left (cm/s)

80 (22)

66 (17)*

63 (15)*

75 (24)¶Ŧ

PSV right (cm/s)

136 (37)

117 (34)*

120 (33)*

129 (42)

PSV left (cm/s)

131 (35)

110 (25)*

107 (24)*

126 (37)¶Ŧ

EDV right (cm/s)

56 (20)

45 (16)*

46 (16)*

51 (22)

EDV left (cm/s)

54 (16)

43 (13)*

41 (11)*

52 (17)¶Ŧ

PI right

1.03 (0.17)

1.08 (0.16)

1.05 (0.23)

1.05 (0.17)

PI left

0.96 (0.15)

1.06 (0.10)

1.07 (0.14)*

1.02 (0.14)

  1. Abbreviations: A Baseline, B Increasing minute ventilation, C Begin moderate hyperventilation with target PaCO2 4–4.7 kPa, D After moderate hyperventilation for 50 min, E Return to baseline. CBFV Mean flow velocity of the middle cerebral artery (cm/s), PSV Peak systolic velocity (cm/s), EDV End-diastolic velocity (cm/s), PI Pulsatility index
  2. * p < 0.05 compared with A
  3. p < 0.05 compared with C
  4. Ŧ p < 0.05 compared with D
  5. N = 11 patients, + = 10 patients. Data are expressed as mean (SD)
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Critical Care

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