Skip to main content

Table 2 Systemic and cerebral hemodynamics

From: Cerebral metabolism is not affected by moderate hyperventilation in patients with traumatic brain injury

n = 11

A

Baseline

B

Minute

ventilation

C

Moderate hyperventilation

D

50 min of moderate hyperventilation

E

Return to baseline

HR (beats/min)

72 (16)

72 (17)

71 (17)

71 (17)

66 (16)

MAP (mmHg)

92 (10)

92 (10)

93 (12)

90 (10)

94 (13)

ICP (mmHg)

16 (6)

8 (5)*

8 (6)*

10 (7)*

14 (6)§¶Ŧ

CPP (mmHg)

77 (9)

84 (9)*

85 (10)*

81 (14)

80 (11)§¶

PbrO2 (mmHg)

32 (10)

33 (9)

33 (10)

30 (8)§¶

30 (8)§

  1. Abbreviations: A Baseline, B Increasing minute ventilation, C Begin moderate hyperventilation with target PaCO2 4–4.7 kPa, D After moderate hyperventilation for 50 min, E Return to baseline, HR Heart rate (beats/min), MAP Mean arterial pressure (mmHg), ICP Intracranial pressure (mmHg), CPP Cerebral perfusion pressure (mmHg), PbrO2 Brain tissue oxygen tension (mmHg)
  2. N = 11 patients; + = 10 patients. Data are expressed as mean (SD)
  3. * p < 0.05 compared with A
  4. § p < 0.05 compared with B
  5. p < 0.05 compared with C
  6. Ŧ p < 0.05 compared with D
Back to article page

Critical Care

ISSN: 1364-8535