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Table 4 Univariate and multivariate analyses for mortality of ECMO

From: Improvement in the survival rates of extracorporeal membrane oxygenation-supported respiratory failure patients: a multicenter retrospective study in Korean patients

Variable

OR (95% CI)

p value

OR (95% CI)

p value

Age (years)

1.043 (1.029, 1.056)

<ā€‰0.001

1.038 (1.022, 1.054)

<ā€‰0.001

Male

0.720 (0.487, 1.064)

0.099

Ā Ā 

Year

0.645 (0.444, 0.939)

0.022

Ā Ā 

Body mass index (kg/m2)

0.982 (0.927, 1.040)

0.527

Ā Ā 

APACHE II score

1.032 (1.010, 1.054)

0.004

Ā Ā 

SOFA score

1.020 (0.978. 1.065)

0.358

Ā Ā 

Immunocompromised

1.335 (0.868, 2.054)

0.188

Ā Ā 

CNS dysfunction

1.274 (0.534, 3.038)

0.585

Ā Ā 

Vasopressor

1.254 (0.857, 1.836)

0.243

Ā Ā 

Corticosteroid

1.914 (1.130, 3.242)

0.016

2.251 (1.153, 4.397)

0.018

Cardiac arrest

1.050 (0.630, 1.747)

0.852

Ā Ā 

CRRT

2.102 (1.233, 3.581)

0.006

2.196 (1.135, 4.247)

0.019

Prone positioning

1.054 (0.705, 1.575)

0.798

Ā Ā 

Nitric oxide

1.853 (1.194, 2.875)

0.006

Ā Ā 

Bicarbonate infusion

1.521 (0.820, 2.820)

0.183

Ā Ā 

Neuromuscular blocker

1.186 (0.821, 1.711)

0.363

Ā Ā 

VV ECMO mode

0.810 (0.456, 1.439)

0.472

Ā Ā 

pH

0.800 (0.244, 2.618)

0.712

Ā Ā 

PaO2 (mmHg)

0.998 (0.993, 1.003)

0.433

Ā Ā 

PaCO2 (mmHg)

1.007 (0.999, 1.015)

0.083

Ā Ā 

PaO2/FiO2

0.999 (0.996, 1.002)

0.447

Ā Ā 

PEEP (cmH2O)

0.968 (0.918, 1.020)

0.219

Ā Ā 

PIP (cmH2O)

1.070 (1.034, 1.107)

<ā€‰0.001

Ā Ā 

Tidal volume (ml/kg)

0.999 (0.998, 1.000)

0.175

Ā Ā 

Driving pressure (cmH2O)

1.078 (1.039, 1.118)

<ā€‰0.001

1.072 (1.031, 1.114)

<ā€‰0.001

Minute ventilation (L/min)

1.022 (0.969, 1.077)

0.428

Ā Ā 

Interval MVā€“ECMO (days)

1.024 (0.998, 1.050)

0.068

Ā Ā 

ECMO duration (days)

1.016 (1.003, 1.029)

0.017

1.020 (1.003, 1.038)

0.021

  1. ECMOĀ extracorporeal membrane oxygenation, OR odds ratio, CI confidence interval, APACHEĀ Acute Physiology and Chronic Health Evaluation, SOFAĀ Sequential Organ Failure Assessment, CNSĀ central nervous system, CRRTĀ continuous renal replacement therapy. VVĀ veno-venous, PaO2Ā partial pressure of oxygen, PaCO2Ā partial pressure of carbon dioxide, FiO2 fraction of inspired oxygen, PEEPĀ positive end-expiratory pressure, PIPĀ peak inspiratory pressure, MVĀ mechanical ventilation