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Table 1 Hematological parameters

From: Intrapulmonary autologous transplant of bone marrow-derived mesenchymal stromal cells improves lipopolysaccharide-induced acute respiratory distress syndrome in rabbit

Hematological parameters

Group

− 24 (h)

0 h

3 h

6 h

12 h

24 h

48 h

72 h

168 h

WBC (/μl)

Treatment

*8240 ± 1469.01

13,760 ± 890.50

*13,040 ± 1228.00

#*12,340 ± 1377.67

#10,740 ± 89.44

#9940 ± 54.77

9580 ± 396.23

9240 ± 1163.18

8700 ± 1437.01

Control

*7720 ± 810.55

13,160 ± 522.49

*13,020 ± 756.30

*12,520 ± 589.06

*12,720 ± 1151.95

*12,620 ± 630.07

*12,640 ± 702.13

*12,380 ± 690.65

*11,740 ± 1040.67

SEG (/μl)

Treatment

*2582 ± 937.64

8355.20 ± 885.64

#*7468.80 ± 1351.25

#*6441.60 ± 279.25

#5814 ± 541

#5098 ± 84.81

#3828.20 ± 246.90

3653.80 ± 205.11

3156.40 ± 1657.72

Control

*2550.20 ± 843.41

8467.60 ± 992.59

*8512.20 ± 599.36

*8101.20 ± 954.74

*7826.60 ± 1288.89

*7739.80 ± 1000.22

*7654.20 ± 1395.41

*7299.40 ± 533.47

*6676.20 ± 450.88

BAND (/μl)

Treatment

27.4 ± 26.43

73 ± 56.74

71.6 ± 66.72

64 ± 58.99

60 ± 56.56

58.8 ± 38

#55.2 ± 40

#44 ± 36.29

#35 ± 22.91

Control

34.8 ± 32.42

73.2 ± 57.99

77.6 ± 49.88

86.2 ± 52.50

89.2 ± 57.47

102 ± 63.80

112.8 ± 81.68

131.2 ± 104.88

*174.8 ± 51.89

LYM (/μl)

Treatment

5173.4 ± 577.66

3363.4 ± 900.92

3480.4 ± 1197.64

3758 ± 664.16

3885.8 ± 606.60

4120.6 ± 743.79

4255.2 ± 891.68

4509 ± 994.02

4906.8 ± 1015.92

Control

4852.4 ± 1214.24

3175.6 ± 882.11

3268 ± 1603.72

3376 ± 813.13

3393.6 ± 1145.60

3471.8 ± 1196.61

3596.2 ± 1301.70

3678.4 ± 1338.22

3795.8 ± 815.30

MON (/μl)

Treatment

86 ± 5.47

76 ± 60.76

80 ± 109.54

78 ± 174.41

76 ± 66.55

80 ± 123.28

78 ± 126.17

78 ± 62.60

#80 ± 77.78

Control

76 ± 4.18

68 ± 8.36

72 ± 97.31

78 ± 83.18

84 ± 85.02

90 ± 108.39

96 ± 108.30

100 ± 70.71

*130 ± 12.24

RBC (×106/μl)

Treatment

6.11 ± 0.21

6.23 ± 0.90

6.28 ± 0.78

6.28 ± 0.67

6.24 ± 1

6.2 ± 0.92

#6.18 ± 0.96

6.13 ± 0.98

6.08 ± 0.99

Control

6.07 ± 0.09

6.21 ± 1.11

6.27 ± 0.91

6.29 ± 1.09

6.32 ± 0.88

6.32 ± 0.86

*6.35 ± 0.09

6.31 ± 1.20

6.24 ± 1.04

Hgb (g/dl)

Treatment

12.12 ± 0.44

12.44 ± 0.56

12.56 ± 1.56

12.48 ± 1.16

12.36 ± 0.51

12.34 ± 1.32

#12.26 ± 0.94

12.2 ± 1.01

12 ± 0.57

Control

12 ± 0.18

12.22 ± 1.46

12.52 ± 1.86

12.72 ± 1.97

12.88 ± 1.6

12.9 ± 1.50

*13.04 ± 0.11

12.86 ± 1.10

12.62 ± 0.52

Hct (%)

Treatment

39.16 ± 2.24

40.66 ± 2.66

40.58 ± 3.20

40.46 ± 2.36

40.18 ± 2.43

40.1 ± 2.87

39.54 ± 2.27

39.3 ± 2.74

39.46 ± 2.08

Control

38.9 ± 2.54

40.4 ± 2.67

40.68 ± 3.29

40.9 ± 4.04

40.94 ± 4.18

41.02 ± 3.54

40.7 ± 3.45

40.52 ± 3.07

40.2 ± 3.29

Plt (×103/μl)

Treatment

371.2 ± 87.08

353 ± 74.24

339 ± 80.56

347.6 ± 64.43

345.6 ± 58.65

361.8 ± 74.88

380.4 ± 75.92

374 ± 66.60

368.4 ± 61.05

Control

339 ± 103.84

330.2 ± 111.21

322.4 ± 78.15

322 ± 104.41

324 ± 42.95

316.8 ± 70.25

337.2 ± 64.13

322.8 ± 74.38

332.4 ± 82.26

  1. Abbreviations: WBC White blood cells, SEG Segmented heterophils, BAND Band heterophils, LYM Lymphocytes, MON Monocytes, RBC Red blood cells, Hgb Hemoglobin, Hct Hematocrit, Plt Platelets
  2. Data are presented as mean ± SD for rabbits in the treatment (acute respiratory distress syndrome [ARDS] + bone marrow mesenchymal stem cells) and control (ARDS + PBS) groups at the different time points of sampling
  3. *p ≤ 0.05; significant compared with inflammation time in the same group
  4. #p ≤ 0.05; significant compared with the control group at the same time