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Table 1 Characteristics of patients

From: Effect of plasma exchange in acute respiratory failure due to Anti-neutrophil cytoplasmic antibody-associated vasculitis

Variable

All patients

n = 12

Female gender

7 (58)

Age (years)

62.1 [49.3–71.6]

Small-vessel vasculitis

 Granulomatosis with polyangiitis

9 (75)

 Microscopic polyangiitis

3 (25)

Vasculitis flare as first manifestation of the disease

11 (92)

Previous maintenance treatments

 Corticosteroids

2 (16)

 Immunosuppressants

6 (50)

Organ involvement at ICU admission

 Pneumo-renal syndrome

9 (75)

 Respiratory SOFA component

3 [2–4]

 PaO2/FiO2 ratio

154 [61–386]

 PaCO2 (mmHg)

35 [31–46]

Acute kidney injury requiring RRT

5 (42)

 Renal SOFA component

2 [1–4]

 Blood creatinine level (μmol/L)

222 [94–450]

 Roteinuria (g/24 h)

1.5 [1.5–3]

 Hemoglobin level (g/dL)

10.1 [8.2–10.7]

Therapeutics received in the ICU

 Number of plasmapheresis courses

6 [4–7]

 Corticosteroids

12 (100)

 Immunosuppressants

12 (100)

 Invasive mechanical ventilation

5 (42)

ICU length of stay (days)a

11 [7–15]

In-ICU mortality

1 (8)

  1. Continuous and categorical variables are described as median [interquartile range] and number (percentage), respectively
  2. aIn-ICU length of stay in patients with and without mechanical invasive ventilation were 15 [9–17] and 7 [4–12] days, respectively (p = 0.03)
  3. RRT renal replacement therapy, SOFA sequential organ failure assessment