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Table 3 Hemodynamic variables during contractility changes

From: Performance comparison of ventricular and arterial dP/dtmax for assessing left ventricular systolic function during different experimental loading and contractile conditions

  Esmolol Dobutamine
Variables Before After Before After
CO, Lmin−1 8.87 ± 1.88 5.15 ± 1.09 8.16 ± 2.01 11.23 ± 3.25
SV, ml 116 ± 13 75 ± 11 111 ± 17 131 ± 22
HR, beatsmin− 1 76 ± 10 69 ± 9 73 ± 10 85 ± 15
MAP, mmHg 73 ± 13 50 ± 4 71 ± 8 83 ± 10
EDV, ml 209 ± 33 200 ± 27 210 ± 28 208 ± 29
ESV ml 93 ± 28 125 ± 22 97 ± 23 74 ± 28
LV Ped, mmHg 15 ± 4 13 ± 3* 14 ± 4 15 ± 4
LV Pes, mmHg 76 ± 15 53 ± 8 73 ± 11 85 ± 12
Ea, mmHgml−1 0.53 ± 0.13 0.55 ± 0.12 0.54 ± 0.13 0.55 ± 0.15
Ees, mmHgml− 1 0.37 ± 0.10 0.23 ± 0.06 0.33 ± 0.07 0.50 ± 0.11
LV ejection fraction, % 56 ± 7 38 ± 5 38 ± 5 53 ± 7
SVV, % 9.4 ± 4.4 17.1 ± 3.6 10.1 ± 3.8 8.9 ± 4.2*
LV dP/dtmax, mmHgs− 1 1067 ± 220 485 ± 58 927 ± 174 1701 ± 384
Femoral dP/dmax, mmHgs− 1 292 ± 57 171 ± 44 287 ± 56 392 ± 70
Radial dP/dtmax, mmHgs− 1 401 ± 142 204 ± 66 391 ± 151 565 ± 192
  1. Data are presented as mean ± SD
  2. LV left ventricle, CO cardiac output, SV stroke volume, HR heart rate, MAP mean arterial pressure, EDV left ventricular end-diastolic volume, ESV left ventricular end-systolic volume, LV Ped left ventricular end-diastolic pressure, LV Pes left ventricular end-systolic pressure, Ees end-systolic elastance, Ea effective arterial elastance, SVV stroke volume variation, dP/dtmax peak rate of pressure
  3. *P < 0.05, P ≤ 0.001, P ≤ 0.0001 vs “before” stage