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Table 1 Hemodynamic variables during afterload changes

From: Performance comparison of ventricular and arterial dP/dtmax for assessing left ventricular systolic function during different experimental loading and contractile conditions

  Phenylephrine Sodium nitroprusside
Variables Before After Before After
CO, Lmin− 1 7.73 ± 1.40 7.07 ± 1.04* 8.09 ± 1.61 9.89 ± 1.49*
SV, ml 105 ± 11 96 ± 12 103 ± 11 119 ± 15
HR, beatsmin− 1 73 ± 11 73 ± 8 79 ± 11 75 ± 11*
MAP, mmHg 80 ± 9 111 ± 13 81 ± 8 55 ± 4
EDV, ml 218 ± 47 214 ± 45 211 ± 43 212 ± 45
ESV ml 110 ± 42 115 ± 41 105 ± 40 89 ± 43
LV Ped, mmHg 13 ± 4 18 ± 4 12 ± 3 7 ± 3
LV Pes, mmHg 84 ± 11 122 ± 15 90 ± 12 60 ± 7
Ea, mmHgml− 1 0.69 ± 0.13 1.09 ± 0.20 0.77 ± 0.16 0.45 ± 0.09
Ees, mmHgml− 1 0.36 ± 0.12 0.48 ± 0.11 0.41 ± 0.14 0.35 ± 0.14
LV ejection fraction, % 52 ± 10 48 ± 9* 52 ± 10 60 ± 13
SVV, % 10.9 ± 3.6 5.8 ± 2.3 10.9 ± 2.5 21.1 ± 5.9
LV dP/dtmax, mmHgs− 1 1003 ± 158 1245 ± 175 1089 ± 157 963 ± 182*
Femoral dP/dmax, mmHgs− 1 306 ± 52 378 ± 53 335 ± 75 226 ± 52
Radial dP/dtmax, mmHgs− 1 480 ± 110 409 ± 69* 463 ± 125 321 ± 96
  1. Data are presented as mean ± SD
  2. LV left ventricle, CO cardiac output, SV stroke volume, HR heart rate, MAP mean arterial pressure, EDV left ventricular end-diastolic volume, ESV left ventricular end-systolic volume, LV Ped left ventricular end-diastolic pressure, LV Pes left ventricular end-systolic pressure, Ees end-systolic elastance, Ea effective arterial elastance, SVV stroke volume variation, dP/dtmax peak rate of pressure
  3. *P < 0.05, P ≤ 0.001, P ≤ 0.0001 vs “before” stage