Fig. 2
From: Angiotensin-(1–7) attenuates organ injury and mortality in rats with polymicrobial sepsis
Angiotensin-(1–7) improves survival after polymicrobial sepsis. Analysis of the survival rate after the administration of angiotensin-(1–7) to rats that underwent sham operation (SOP, n = 6), SOP plus angiotensin-(1–7) administration (1 mg/kg at 3 and 6 h after SOP procedure [SOP-Ad], n = 6), cecal ligation and puncture (CLP, n = 22), CLP plus angiotensin-(1–7) administration (1 mg/kg at 3 h after CLP procedure [CLP-As], n = 6), and CLP plus angiotensin-(1–7) administration (1 mg/kg at 3 and 6 h after CLP procedure [CLP-Ad], n = 12). Survival time was measured for 24 h. Survival distribution was compared using the log-rank test and represented by Kaplan-Meier curves. Data are expressed as percentage of rats that survived at the end of the experiment. *p < 0.05 CLP. vs. SOP. ##p < 0.01 CLP-Ad vs. CLP