|  | APPROVE | MEWS | NEWS | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Cutoff > 0.15 | Cutoff > 0.20 | Cutoff > 0.25 | Cutoff > 4 | Cutoff > 5 | Cutoff > 6 | Cutoff > 4 | Cutoff > 5 | Cutoff > 6 | ||
2013a | Sensitivity (95% CI) | 0.75 (0.72–0.77) | 0.69 (0.66–0.71) | 0.63 (0.60–0.66) | 0.16 (0.13–0.18) | 0.08 (0.07–0.11) | 0.04 (0.03–0.06) | 0.28 (0.25–0.31) | 0.22 (0.19–0.25) | 0.16 (0.13–0.18) |
Specificity (95% CI) | 0.83 (0.83–0.83) | 0.88 (0.88–0.89) | 0.92 (0.92–0.92) | 0.98 (0.98–0.98) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.94 (0.94–0.94) | 0.97 (0.97–0.97) | 0.99 (0.98–0.99) | |
Positive predictive value (95% CI) | 0.13 (0.12–0.14) | 0.17 (0.16–0.18) | 0.21 (0.19–0.22) | 0.19 (0.16–0.22) | 0.37 (0.30–0.44) | 0.54 (0.42–0.66) | 0.11 (0.10–0.13) | 0.16 (0.14–0.18) | 0.22 (0.19–0.25) | |
Negative predictive value (95% CI) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.98 (0.98–0.98) | 0.98 (0.97–0.98) | 0.98 (0.97–0.98) | 0.98 (0.98–0.98) | 0.98 (0.98–0.98) | 0.98 (0.98–0.98) | |
False positive rate (95% CI) | 0.17 (0.17–0.17) | 0.12 (0.11–0.12) | 0.08 (0.08–0.08) | 0.02 (0.02–0.02) | 0.01 (0.01–0.01) | 0.01 (0.01–0.01) | 0.06 (0.06–0.06) | 0.03 (0.03–0.03) | 0.01 (0.01-0.01) | |
2017b | Sensitivity (95% CI) | 0.89 (0.74–0.97) | 0.69 (0.52–0.84) | 0.64 (0.46–0.79) | 0.67 (0.49–0.81) | 0.39 (0.23–0.57) | 0.19 (0.08–0.36) | 0.67 (0.49–0.81) | 0.47 (0.30–0.65) | 0.39 (0.23–0.57) |
Specificity (95% CI) | 0.85 (0.83–0.86) | 0.91 (0.90–0.92) | 0.95 (0.94–0.96) | 0.86 (0.85–0.88) | 0.96 (0.95–0.97) | 0.99 (0.99–0.99) | 0.75 (0.73–0.76) | 0.86 (0.85–0.88) | 0.93 (0.92–0.94) | |
Positive predictive value (95% CI) | 0.09 (0.06–0.12) | 0.11 (0.07–0.16) | 0.16 (0.11–0.23) | 0.07 (0.05–0.11) | 0.15 (0.08–0.23) | 0.29 (0.13–0.51) | 0.04 (0.03–0.06) | 0.05 (0.03–0.08) | 0.08 (0.05–0.14) | |
Negative predictive value (95% CI) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.99 (0.99–0.99) | 0.99 (0.98–0.99) | 0.99 (0.98–0.99) | 0.99 (0.99–0.99) | 0.99 (0.98–0.99) | 0.99 (0.98–0.99) | |
False positive rate (95% CI) | 0.15 (0.13–0.16) | 0.09 (0.08–0.10) | 0.05 (0.04–0.06) | 0.14 (0.12–0.15) | 0.04 (0.03–0.04) | 0.01 (0.00–0.01) | 0.25 (0.23–0.27) | 0.14 (0.12–0.15) | 0.07 (0.06–0.08) |