Table 3 Microbiologic blood culture results and initial antibiotics use among patients with severe sepsis
Microbiological results of blood cultures | n = 560 |
 Gram-negative | |
 E. coli | 182 (32.5) |
 Klebsiella | 72 (12.9) |
 Pseudomonas | 16 (2.9) |
 Gram-positive | |
 Staphylococci | 91 (16.3) |
 Streptococci | 109 (19.5) |
 MRSA | 16 (2.9) |
 Enterococcus | 25 (4.5) |
 Anaerobic | 24 (4.3) |
 Fungi | 14 (2.5) |
Antibiotics | n = 1140 |
 Penicillin derivative (PCG, ABPC, ABPC/MCIPC) | 30 (2.6) |
 Ampicillin/sulbactam | 78 (6.8) |
 PIPC/TAZ | 238 (20.9) |
 Sulbactam/cefoperazone | 11 (1.0) |
 First-generation cephalosporin | 28 (2.5) |
 Second-generation cephalosporin (CTM, CMZ, FMOX) | 32 (2.8) |
 Third-generation cephalosporin (CTX, CPZ, CTRX) | 99 (8.7) |
 Third-generation cephalosporin against pseudomonas | 4 (0.4) |
 Fourth generation cephalosporin against pseudomonas | 26 (2.3) |
 Carbapenem | 627 (55.0) |
 Aminoglycoside | 8 (0.7) |
 Quinolone | 19 (1.7) |
 Tetracycline | 7 (0.6) |
 Macrolide | – |
 Metronidazole | 12 (1.1) |
 CLDM | 48 (4.2) |
 Vancomycin | 203 (17.8) |
 Other anti-methicillin-resistant Staphylococcus aureus drugs | 67 (5.9) |
 Antifungals | 50 (4.4) |
 Others | 83 (7.3) |