Table 5 Genotype and allele frequencies distribution in 28-day surviving and non-surviving patients with sepsis
IL-27 | Survivors n (%) | Non-survivors n (%) | P | P* | OR (95% CI) |
|---|---|---|---|---|---|
rs153109 | |||||
AA | 235 (35.1) | 99 (45.8) | 0.019 | 0.025 | – |
GA | 321 (48.0) | 87 (40.3) | – | – | – |
GG | 113 (16.9) | 30 (13.9) | – | – | – |
AA/GA | 556 (83.1) | 186 (86.1) | 0.297 | 0.297 | 0.794 (0.513–1.227) |
GA/GG | 434 (64.9) | 117 (54.2) | 0.005 | 0.020 | 1.563 (1.145–2.133) |
A | 791 (59.1) | 285 (66.0) | – | – | 1.000 (reference) |
G | 547 (40.9) | 147 (34.0) | 0.011 | 0.022 | 1.341 (1.068–1.682) |
rs17855750 | |||||
TT | 237 (78.7) | 75 (73.5) | 0.311 | 0.311 | – |
GT | 59 (19.6) | 23 (22.6) | – | – | – |
GG | 5 (1.7) | 4 (3.9) | – | – | – |
TT/GT | 296 (98.3) | 98 (96.1) | 0.239 | 0.311 | 2.416 (0.636-9.180) |
GT/GG | 64 (21.3) | 27 (26.5) | 0.277 | 0.311 | 0.750 (0.446-1.261) |
T | 533 (88.5) | 173 (84.8) | – | – | 1.000 (reference) |
G | 69 (11.5) | 31 (15.2) | 0.162 | 0.311 | 0.722 (0.457-1.141) |