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Table 3 Genotype and allele frequencies distribution of the IL-27 rs17855750 polymorphism in the cases and controls

From: The interleukin-27 -964A>G polymorphism enhances sepsis-induced inflammatory responses and confers susceptibility to the development of sepsis

IL-27

Sepsis n = 403 (%)

Control n = 400 (%)

P

P*

OR (95% CI)

TT

312 (77.4)

315 (78.7)

0.719

0.719

–

TG

82 (20.4)

79 (19.8)

–

–

–

GG

9 (2.2)

6 (1.5)

–

–

–

TT/TG

394 (97.8)

394 (98.5)

0.443

0.719

0.67 (0.24-1.89)

TG/GG

91 (22.6)

85 (21.3)

0.649

0.719

1.08 (0.77-1.51)

T

706 (87.6)

709 (88.6)

–

–

1.000 (reference)

G

100 (12.4)

91 (11.4)

0.523

0.719

1.10 (0.82-1.49)

  1. OR odds ratio, 95% CI 95% confidence interval
  2. *False discovery rate-adjusted P value for multiple hypotheses testing using the Benjamini-Hochberg method
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Critical Care

ISSN: 1364-8535