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Table 3 Multivariate analysis of the in-hospital mortality and prognostic scoring system at day 2 (n = 248)

From: An early increase in endothelial protein C receptor is associated with excess mortality in pneumococcal pneumonia with septic shock in the ICU

Prognostic markers

Logistic regression

Scoring system

Odds ratio

P value

95% CI

Weight

sEPCR log at day 1 (ng/mL)

1.95

0.0407

[1.03–3.70]

0.289

delta sEPCR (day 2 - day 1, ng/mL)

1.01

0.0323

[1.00–1.03]

0.269

Age (years)

1.03

0.0586

[1.00–1.05]

0.293

McCabe score at day 1

0.52

0.1833

[0.19–1.37]

−0.014

Gender, male versus female

2.02

0.0586

[0.97–4.19]

0.384

Fine’s score (log)

2.94

0.1928

[0.73–11.8]

0.341

SOFA score at day 1 (square)

1.01

0.0199

[1.00–1.01]

0.441

SAPS II

1.02

0.2136

[0.99–1.04]

0.257

  1. The scoring system and the multivariate analysis were based on least absolute shrinkage and selection operator (lasso) logistic regression. The prognostic score was the sum of the product between the weights and the normalized explicative variables
  2. sEPCR soluble endothelial protein C receptor, SOFA Sepsis-related Organ Failure Assessment, SAPS Simplified Acute Physiology Score
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Critical Care

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