|
Prognostic markers
|
Logistic regression
|
Scoring system
|
|---|
|
Odds ratio
|
P value
|
95% CI
|
Weight
|
|---|
|
sEPCR log at day 1 (ng/mL)
|
1.95
|
0.0407
|
[1.03–3.70]
|
0.289
|
|
delta sEPCR (day 2 - day 1, ng/mL)
|
1.01
|
0.0323
|
[1.00–1.03]
|
0.269
|
|
Age (years)
|
1.03
|
0.0586
|
[1.00–1.05]
|
0.293
|
|
McCabe score at day 1
|
0.52
|
0.1833
|
[0.19–1.37]
|
−0.014
|
|
Gender, male versus female
|
2.02
|
0.0586
|
[0.97–4.19]
|
0.384
|
|
Fine’s score (log)
|
2.94
|
0.1928
|
[0.73–11.8]
|
0.341
|
|
SOFA score at day 1 (square)
|
1.01
|
0.0199
|
[1.00–1.01]
|
0.441
|
|
SAPS II
|
1.02
|
0.2136
|
[0.99–1.04]
|
0.257
|
- The scoring system and the multivariate analysis were based on least absolute shrinkage and selection operator (lasso) logistic regression. The prognostic score was the sum of the product between the weights and the normalized explicative variables
- sEPCR soluble endothelial protein C receptor, SOFA Sepsis-related Organ Failure Assessment, SAPS Simplified Acute Physiology Score
