Table 1 Fragility index calculated for the study included in the systematic review and meta-analysis by Chu et al. [1]
Study | Setting | Liberal group (FiO2 0.52 CI:0.39-0.85) | Conservative group (FiO2 0.21 CI:0.21-0.50) | p value for mortality in each study | Fragility index n (p) |
|---|---|---|---|---|---|
Ali et al. (2014) [6] | Stroke | 5/155 | 4/146 | 0.99 | 0 (1) |
Roffe et al. (2017) [7] | Stroke | 50/2668 | 45/2668 | 0.75 | 0 (0.506) |
Ronning et al. (1999) [8] | Stroke | 36/292 | 27/258 | 0.54 | 0 (0.506) |
Singhal et al. (2005) [9] | Stroke | 0/9 | 1/7 | NS | 0 (0.438) |
NCT00414726 | Stroke | 14/43 | 4/42 | 0.08 | 2 (0.072) |
Shi et al. (2017) [10] | Stroke | 0/9 | 0/9 | NS | 0 (1) |
NCT02378454 (2015) | Sepsis | 3/25 | 2/25 | NS | 0 (1) |
Butler et al. (1987) [11] | Limb ischemia | 1/17 | 0/22 | NS | 0 (0.436) |
Schietroma et al. (2016) [12] | Perforated peptic ulcer | 2/119 | 4/120 | 0.42 | 0 (0648) |
NCT02687217 | Acute appendicitis | 0/30 | 0/30 | NS | 0 (1) |
Girardis et al. (2016) [5] | Critical illness | 80/243 | 58/235 | 0.01 | 0 (0.055) |
Panwar et al. (2016) [13] | Critical illness | 12/51 | 13/53 | 0.44 | 0 (1) |
Hofmann et al. (2017) [14] | Myocardial infarction | 53/3311 | 44/3318 | 0.08 | 0 (0.359) |
Khoshnood et al. (2015) [15] | Myocardial infarction | 3/85 | 3/75 | NS | 0 (1) |
Kuisma et al. (2006) [16] | Cardiac arrest | 4/14 | 4/14 | NS | 0 (1) |
Rawles et al. (1976) [17] | Myocardial infarction | 9/105 | 3/95 | NS | 0 (0.140) |
Stub et al. (2012) [18] | Myocardial infarction | 5/132 | 11/132 | NS | 0 (0.204) |
Ukholkina et al. (2005) [19] | Myocardial infarction | 1/58 | 0/79 | NS | 0 (0.428) |
Young et al. (2014) [20] | Cardiac arrest | 5/9 | 4/8 | NS | 0 (1) |