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Table 2 Multivariable analysis of factors associated with having ARDS

From: Identifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database

Variable Odds ratio (95% CI) p value
 Diabetes mellitus diagnosis 0.93 (0.78, 1.11) 0.39
 Baseline PaO2:FiO2 ratio (mmHg) 0.996 (0.994, 0.997) < 0.0001
 Baseline respiratory rate (breaths/min) 1.03 (1.02, 1.04) < 0.0001
 Baseline PEEP (cmH2O) 1.06 (1.04, 1.11) < 0.0001
 Baseline peak inspiratory pressure (cmH2O) 1.02 (1.01, 1.03) 0.0001
ARDS risk factorsa
 Pulmonary risk factors 1.93 (1.53, 2.45) < 0.0001
 Non-pulmonary risk factors 1.50 (1.15, 1.95) 0.003
 Pulmonary and non-pulmonary risk factors 1.89 (1.40, 2.53) < 0.0001
COPD or home ventilation 0.78 (0.65, 0.93) 0.005
Haematologic neoplasm 1.60 (1.02, 2.52) 0.04
  1. Analysis based on data from 3814 observations
  2. Abbreviations: ARDS acute respiratory distress syndrome, CI confidence interval, COPD chronic obstructive pulmonary disease, PEEP positive end-expiratory pressure
  3. aTo estimate the odds ratio, the reference category is “No risk factor”
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Critical Care

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