Table 2 Multivariate analysis by Cox regression to adjust prognostic scores with confounders associated with 28-day mortality

Parameter

HR

p Value

Parameter

HR

p Value

Parameter

HR

p Value

MELD score

1.05 (95% CI 1.03–1.07)

< 0.0001

Child-Pugh score

1.35 (95% CI 1.20–1.53)

< 0.0001

CLIF-C ACLF score

1.07 (95% CI 1.05–1.09)

< 0.0001

Age (years)

1.01 (95% CI 1.00–1.03)

0.12

Age (years)

1.02 (95% CI 1.00–1.04)

0.04

Albumin (g/L)

0.98 (95% CI 0.95–1.01)

0.17

Albumin (g/L)

0.99 (95% CI 0.96–1.02)

0.41

Platelet count (10⁹/L)

0.97 (95% CI 0.99–1.00)

0.04

Platelet count (10⁹/L)

1.00 (95% CI 0.99–1.00)

0.07

Platelet count (10⁹/L)

0.99 (95% CI 0.99–1.00)

0.002

HE (0–2/3–4)

1.31 (95% CI 0.80–2.15)

0.29