Table 1 Clinical parameters according to survival status after 28 days

Male sex, n (%)

70 (68%)

66 (67%)

p = 0.85

Age, years

50 ± 12

53 ± 11

p = 0.19

MELD score

23 ± 9

30 ± 10

p < 0.0001

Child-Pugh score

10.5 ± 1.7

11.9 ± 1.6

p < 0.0001

Child-Pugh classification, A/B/C, n (%)^a

2/28/73 (2%/27%/71%)

0/8/90 (0%/8%/92%)

p = 0.001

CLIF-OF score

11 (9–12)

13 (11–14)

p < 0.0001

CLIF-C ACLF score

50.6 ± 7.3

58.4 ± 9.6

p < 0.0001

Number of organ failures, 1–3/4–6, n (%)

101/2 (98%/2%)

77/22 (78%/22%)

p < 0.0001

Renal replacement, n (%)

26 (25%)

41 (41%)

p = 0.02

HE classification, 0–2/3–4^b, n (%)

91/12 (88%/12%)

78/21 (79%/21%)

p = 0.07

Bilirubin, mg/dl; μmol/L

3.4 (1.6–9.1); 58 (27–156)

7.8 (3.5–15.5); 133 (60–265)

p < 0.001

INR

1.8 (1.5–2.3)

2.2 (1.9–3.1)

p < 0.0001

Albumin, g/dl; g/L

2.6 ± 0.7; 26 ± 7

2.5 ± 0.7; 25 ± 7

p = 0.23

Platelet count, 10⁹/L

87 (57–137)

80 (53–119)

p = 0.17

Sodium, mmol/L

138 ± 9

137 ± 10

p = 0.20

Serum creatinine, mg/dl; μmol/L

0.9 (0.7–1.6); 80 (62–142)

1.5 (0.9–2.4); 133 (80–212)

p = 0.002

WBC count, 10⁹/L

9.4 (6.3–15.1)

10.2 (6.3–16.5)

p = 0.37