Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis

Table 3 Effect of decompressive laparotomy on organ function in adults (all patients)

Variable	No. of studies reporting data of variables	Mean preoperative value	Mean postoperative value	Mean difference following DL	Heterogeneity			Hedges’ g	p Value
Variable	No. of studies reporting data of variables	Mean preoperative value	Mean postoperative value	Mean difference following DL	Cochran’s Q	df	p Value	Hedges’ g	p Value
IAP (mmHg)	8	31.7 ± 6.4	13.5 ± 3.0	− 18.2 ± 6.5	56.373	7	< 0.001	2.222	< 0.001
HR (beats/min)	4	122 ± 10.6	109 ± 11.6	− 12.2 ± 9.5	7.623	3	0.054	0.505	0.040
MAP (mmHg)	5	82 ± 16.3	88.8 ± 21.7	+ 6.8 ± 15.7	40.398	4	< 0.001	0.173	0.698
CVP (mmHg)	6	18.6 ± 3.1	14 ± 2.9	− 4.6 ± 2.3	13.030	5	0.023	0.624	0.022
PCWP (mmHg)	5	23.7 ± 6.7	17.9 ± 3.7	− 5.8 ± 5	41.008	4	< 0.001	1.117	0.029
CI (L/min/m²)	6	4 ± 1.2	4.6 ± 1.5	+ 0.82 ± 0.8	8.145	5	0.148	0.569	0.002
SVRI (dyn·s/cm⁵·m²)	3	2009.3 ± 364.5	1484 ± 451.2	311.3 ± 539.4	42.86	2	< 0.001	0.534	0.28
PIP (cmH₂O)	9	45.5 ± 8.7	35.6 ± 8.0	− 10.1 ± 3.9	22.310	8	0.004	1.344	< 0.001
PEEP (cmH₂O)	2	18.2 ± 13.1	17.4 ± 13.2	− 0.9 ± 0.1	0.002	1	0.966	0.078	0.768
P/F ratio	8	163.7 ± 48.4	234.1 ± 55.8	+ 70.4 ± 49.4	11.889	7	0.104	0.894	< 0.001
UO (ml/h)	8	44.1 ± 30.0	139.4 ± 109.4	+ 95.3 ± 105.3	23.687	7	0.001	1.061	< 0.001

Abbreviations: IAP Intra-abdominal pressure, HR Heart rate, MAP Mean arterial pressure, CVP Central venous pressure, PCWP Pulmonary capillary wedge pressure, CI Cardiac index, SVRI Systemic vascular resistance index, PIP Peak inspiratory pressure, PEEP Positive end-expiratory pressure, P/F ratio Ratio of partial pressure arterial oxygen and fraction of inspired oxygen, UO Urinary output

ISSN: 1364-8535