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Table 6 Univariate and multivariate analyses of risk factors of intensive care unit (ICU) death in the study population

From: Clinical characteristics and prognosis of bacteraemia during postoperative intra-abdominal infections

 

Univariate analysis

Multivariate analysis

Parameters

Odds ratio

95% CI

p value

Odds ratio

95% CI

p value

Demographic characteristics and underlying diseases

 Age > 62 years

2.45

(1.55–3.90)

< 0.001

   

 McCabe Fatal

1.55

(0.96–2.49)

0.08

  

 Immunosuppression or cancer

1.83

(1.15–2.92)

0.01

  

 Urgent initial surgery

2.04

(1.29–3.23)

0.002

2.71

(1.53–4.81)

0.0006

Severity criteria at the time of reoperation

 Small bowel perforation

1.57

(0.95–2.59)

0.07

   

 SAPS II > 47 at reoperation

4.26

(2.61–6.94)

< 0.001

4.78

(2.71–8.45)

< 0.0001

Blood and peritoneal microbiological results

 Bacteraemia

1.48

(0.84–2.59)

0.16

1.62

(0.81–3.24)

0.169

Peritoneal samples involving

 Enterococci

1.71

(1.08–2.69)

0.019

   

 Non-fermenting Gram-negative Bacteria

2.01

(1.13–3.65)

0.019

  

 Streptococci

0.54

(0.30–0.96)

0.037

  

Empirical and documented therapies

 Empirical imipenem therapy

1.66

(1.01–2.72)

0.044

   

 Empirical vancomycin therapy

1.56

(0.99–2.46)

0.050

  

 Empirical antifungal therapy

1.72

(1.08–2.74)

0.019

2.91

(1.62–5.22)

0.0003

 De-escalation documented therapy

0.54

(0.34–0.85)

0.007

0.50

(0.28–0.89)

0.018

 Documented therapy using piperacillin/tazobactam

1.74

(1.09–2.78)

0.018

   

 Documented antifungal therapy

1.67

(1.05–2.63)

0.026

  
  1. The model was adjusted on year of admission
  2. Multivariate logistic regression with stepwise selection: the C-index for the model was 0.81 95% CI 0.76–0.86, the Hosmer-Lemeshow test p value was 0.02
  3. CI confidence interval, SAPS Simplified Acute Physiology Score