| Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
Parameters | Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value |
Demographic characteristics and underlying diseases | ||||||
 Age > 62 years | 2.45 | (1.55–3.90) | < 0.001 |  |  |  |
 McCabe Fatal | 1.55 | (0.96–2.49) | 0.08 |  |  | |
 Immunosuppression or cancer | 1.83 | (1.15–2.92) | 0.01 |  |  | |
 Urgent initial surgery | 2.04 | (1.29–3.23) | 0.002 | 2.71 | (1.53–4.81) | 0.0006 |
Severity criteria at the time of reoperation | ||||||
 Small bowel perforation | 1.57 | (0.95–2.59) | 0.07 |  |  |  |
 SAPS II > 47 at reoperation | 4.26 | (2.61–6.94) | < 0.001 | 4.78 | (2.71–8.45) | < 0.0001 |
Blood and peritoneal microbiological results | ||||||
 Bacteraemia | 1.48 | (0.84–2.59) | 0.16 | 1.62 | (0.81–3.24) | 0.169 |
Peritoneal samples involving | ||||||
 Enterococci | 1.71 | (1.08–2.69) | 0.019 |  |  |  |
 Non-fermenting Gram-negative Bacteria | 2.01 | (1.13–3.65) | 0.019 |  |  | |
 Streptococci | 0.54 | (0.30–0.96) | 0.037 |  |  | |
Empirical and documented therapies | ||||||
 Empirical imipenem therapy | 1.66 | (1.01–2.72) | 0.044 |  |  |  |
 Empirical vancomycin therapy | 1.56 | (0.99–2.46) | 0.050 |  |  | |
 Empirical antifungal therapy | 1.72 | (1.08–2.74) | 0.019 | 2.91 | (1.62–5.22) | 0.0003 |
 De-escalation documented therapy | 0.54 | (0.34–0.85) | 0.007 | 0.50 | (0.28–0.89) | 0.018 |
 Documented therapy using piperacillin/tazobactam | 1.74 | (1.09–2.78) | 0.018 |  |  |  |
 Documented antifungal therapy | 1.67 | (1.05–2.63) | 0.026 |  |  |