Table 5 Clinical outcome in bacteraemic and non-bacteraemic patients
Clinical outcomes | Bacteraemic patients (n = 64) | Patients without bacteraemia (n = 279) | Odds ratio | 95% CI | p value |
|---|---|---|---|---|---|
On day 3 after surgery for PIAI | |||||
 Temperature ≥ 36 °C and ≤ 38 °C, n (%) | 25/55 (45.4) | 165/243 (67.9) | 0.39 | (0.21–0.71) | < 0.01 |
 WBC count ≥ 5000 and ≤ 15,000/mm3, n (%) | 20/55 (57.1) | 108/243 (44.4) | 0.71 | (0.39–1.31) | 0.27 |
 SOFA score ≤ 3 points, n (%) | 22/55 (40) | 104/243 (42.8) | 0.89 | (0.49–1.62) | 0.70 |
 All three criteria, n (%) | 7/55 (12.7) | 42/243 (17.3) | 0.69 | (0.29–1.64) | 0.54 |
Delta SOFA between day 3 and day 0, median (IQR) | 1 (0–4) | 2 (0–4) | 1.00a | (0.91–1.11) | 0.82 |
On day 7 after surgery for PIAI | |||||
 Temperature ≥ 36 °C and ≤ 38 °C, n (%) | 29/44 (65.9) | 140/200 (70) | 0.82 | (0.41–1.65) | 0.59 |
 WBC count ≥ 5000 and ≤ 15,000/mm3, n (%) | 23/44 (52.3) | 84/200 (42) | 1.51 | (0.78–2.91) | 0.21 |
 SOFA score ≤ 3 points, n (%) | 22/44 (50) | 112/200 (56) | 0.78 | (0.41–1.51) | 0.46 |
 All three criteria, n (%) | 12/44 (27.3) | 44/200 (22) | 1.33 | (0.63–2.79) | 0.45 |
Delta SOFA between day 7 and day 0, median (IQR) | 3.5 (1.2–6) | 4 (1–6) | 0.98a | (0.89–1.11) | 0.93 |
Suspected persistent sepsis, n (%) | 36 (58) | 144 (53) | 1.21 | (0.69–2.11) | 0.50 |
Reoperation, n (%) | 29 (45) | 122 (44) | 1.02 | (0.59–1.76) | 0.81 |
Total number of reoperations, median (IQR) | 1 (1–2) | 2 (1–2) | 0.88 | (0.71–1.10) | 0.21 |
Interval between surgery for PIAI and reoperation, median (IQR) | 5 (2.5–7) | 5 (2–8) | 0.97 | (0.87–1.08) | 0.42 |
Main reasons for reoperation | |||||
 Septic shock/multiple organ failure, n (%) | 11/29 (38) | 47/122 (39) | 0.97 | (0.42–2.24) | 0.95 |
 Sepsis, n (%) | 18/29 (62) | 75/122 (62) | 1.02 | (0.44–2.36) | 0.95 |
 Haemorrhage, n (%) | 2/29 (7) | 9/122 (7) | 0.93 | (0.18–4.55) | 1 |
 Suspicion of bowel ischaemia, n (%) | 2/29 (7) | 26/122 (21) | 0.27 | (0.06–1.22) | 0.11 |
Main intraoperative diagnoses at reoperation | |||||
 Anastomotic leak, n (%) | 8/29 (28) | 29/122 (24) | 1.22 | (0.48–3.04) | 0.64 |
 Bowel perforation, n (%) | 4/29 (14) | 25/122 (20) | 0.62 | (0.19–1.94) | 0.60 |
 Ischaemia, n (%) | 2/29 (7) | 23/122 (19) | 0.31 | (0.07–1.43) | 0.17 |
 Abscess or collections, n (%) | 5/29 (17) | 14/122 (11) | 1.60 | (0.53–4.89) | 0.37 |
 No identified cause, n (%) | 5/29 (17) | 10/122 (8) | 2.33 | (0.73–7.44) | 0.16 |
Medical complications, n (%) | 5 (8) | 37 (14) | 0.55 | (0.20–1.47) | 0.29 |
Duration of mechanical ventilation, median (IQR), daysb | 8 (4–15) | 7 (3–15) | 1.45 | (0.71–2.95) | 0.75 |
ICU stay, median (IQR), daysb | 12 (8–23) | 15 (8–25) | 0.96 | (0.48–1.94) | 0.39 |
Death in ICU, n (%) | 26 (41) | 82 (29) | 1.64 | (0.94–2.88) | 0.08 |
Death in hospital, n (%) | 26 (41) | 88 (32) | 1.48 | (0.85–2.59) | 0.16 |