| |
Burn ≥ 50% TBSA
| |
Burn ≥ 80% TBSA
| |
|---|
|
Control (n = 36)
|
HVHF (n = 36)
|
p Value
|
Control (n = 17)
|
HVHF (n = 16)
|
p Value
|
|---|
|
Mortality
|
|
28-day, n (%)
|
9 (25.0)
|
5 (13.9)
|
0.37
|
7 (41.2)
|
4 (25.0)
|
0.46
|
|
60-day, n (%)
|
13 (36.1)
|
6 (16.7)
|
0.11
|
10 (58.8)
|
4 (25.0)
|
0.08
|
|
90-day, n (%)
|
15 (41.7)
|
6 (16.7)a
|
0.04
|
11 (64.7)
|
4 (25.0)a
|
0.04
|
|
Sepsis, n (%)
|
19 (52.8)
|
10 (27.8)
|
0.05
|
13 (76.5)
|
6 (37.5)a
|
0.04
|
|
Septic shock, n (%)
|
16 (44.4)
|
5 (13.9)a
|
0.01
|
11 (64.7)
|
3 (18.8)a
|
0.01
|
|
Duration of MV (days)
|
9.5 (7.0, 11.8)
|
7.0 (5.0, 10.0)
|
0.06
|
10.0 (7.0, 18.0)
|
7.0 (2.0, 8.0)a
|
0.03
|
|
ICU days
|
30.0 (20.5, 48.8)
|
34.0 (15.5, 53.0)
|
0.70
|
31.0 (24.5, 54.0)
|
51.5 (22.3, 78.3)
|
0.26
|
|
Duration of vasopressors (days)
|
4.0 (2.0, 11.3)
|
1.0 (1.0, 2.0)a
|
0.005
|
2.0 (4.0, 11.3)
|
1.0 (1.0, 2.0)a
|
0.005
|
- Abbreviations: TBSA Total burn surface area, MV Mechanical ventilation, ICU Intensive care unit, HVHF High-volume haemofiltration
- Data are presented as mean ± SD, median (25th and 75th quantiles) or percentages. Patients with complete data were included in outcomes comparison via the per-protocol analysis
- a p < 0.05 indicates a significant difference compared with the control group
