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Table 3 Outcomes of patients in high-volume haemofiltration and control groups in per-protocol analysis

From: Early application of continuous high-volume haemofiltration can reduce sepsis and improve the prognosis of patients with severe burns

  Burn ≥ 50% TBSA   Burn ≥ 80% TBSA  
Control (n = 36) HVHF (n = 36) p Value Control (n = 17) HVHF (n = 16) p Value
Mortality
 28-day, n (%) 9 (25.0) 5 (13.9) 0.37 7 (41.2) 4 (25.0) 0.46
 60-day, n (%) 13 (36.1) 6 (16.7) 0.11 10 (58.8) 4 (25.0) 0.08
 90-day, n (%) 15 (41.7) 6 (16.7)a 0.04 11 (64.7) 4 (25.0)a 0.04
Sepsis, n (%) 19 (52.8) 10 (27.8) 0.05 13 (76.5) 6 (37.5)a 0.04
Septic shock, n (%) 16 (44.4) 5 (13.9)a 0.01 11 (64.7) 3 (18.8)a 0.01
Duration of MV (days) 9.5 (7.0, 11.8) 7.0 (5.0, 10.0) 0.06 10.0 (7.0, 18.0) 7.0 (2.0, 8.0)a 0.03
ICU days 30.0 (20.5, 48.8) 34.0 (15.5, 53.0) 0.70 31.0 (24.5, 54.0) 51.5 (22.3, 78.3) 0.26
Duration of vasopressors (days) 4.0 (2.0, 11.3) 1.0 (1.0, 2.0)a 0.005 2.0 (4.0, 11.3) 1.0 (1.0, 2.0)a 0.005
  1. Abbreviations: TBSA Total burn surface area, MV Mechanical ventilation, ICU Intensive care unit, HVHF High-volume haemofiltration
  2. Data are presented as mean ± SD, median (25th and 75th quantiles) or percentages. Patients with complete data were included in outcomes comparison via the per-protocol analysis
  3. a p < 0.05 indicates a significant difference compared with the control group