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Table 2 Fibrinogen levels over time, by treatment arm

From: Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Outcome

Fibrinogen concentrate arm (n = 24)

Placebo arm (n = 24)

Overall (n = 48)

p Value

Fibrinogen, mean (SD)

 At admission

1.6 (0.7)

2.1 (0.9)

1.9 (0.8)

n/a

 At 2 h from admission during first active haemorrhagea

2.8 (1.3)

1.8 (0.6)

2.3 (1.1)

< 0.0001

 7 days from admission

6.7 (1.8)

7.5 (1.9)

7.1 (1.9)

0.2843

  1. aP value adjusted for value at admission
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Critical Care

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