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Table 2 Fibrinogen levels over time, by treatment arm

From: Early fibrinogen concentrate therapy for major haemorrhage in trauma (E-FIT 1): results from a UK multi-centre, randomised, double blind, placebo-controlled pilot trial

Outcome Fibrinogen concentrate arm (n = 24) Placebo arm (n = 24) Overall (n = 48) p Value
Fibrinogen, mean (SD)
 At admission 1.6 (0.7) 2.1 (0.9) 1.9 (0.8) n/a
 At 2 h from admission during first active haemorrhagea 2.8 (1.3) 1.8 (0.6) 2.3 (1.1) < 0.0001
 7 days from admission 6.7 (1.8) 7.5 (1.9) 7.1 (1.9) 0.2843
  1. aP value adjusted for value at admission