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Table 1 Baseline characteristics of treatment groups

From: The effect of polymyxin B hemoperfusion on modulation of human leukocyte antigen DR in severe sepsis patients

Characteristic PMX-HP group (n = 29) Non-PMX-HP group (n = 30) P valuea
Age (years), mean (SD) 70.2 (13.0) 67.4 (14.6) 0.43
Male, n (%) 23 (79) 17 (57) 0.06
BMI (kg/m2), mean (SD) 24.2 (4.3) 23.5 (4.7) 0.62
Baseline serum creatinine (mg/dl), median (Q1, Q3) 1.0 (1.0, 1.1) 1.0 (0.8, 1.1) 0.48
BUN at enrollment (mg/dl), median (Q1, Q3) 41 (26, 63) 41 (22, 62) 0.65
Serum creatinine at enrollment (mg/dl), median (Q1, Q3) 2.2 (1.6, 3.1) 2.6 (1.8, 4.0) 0.34
AKI, n (%)    0.16
 Non-AKI 4 (14) 5 (17)  
 Stage 1 8 (28) 4 (13)  
 Stage 2 9 (31) 5 (17)  
 Stage 3 8 (28) 16 (53)  
RRT, n (%) 27 (93) 20 (69) 0.02
  CRRT 21 (72%) 14 (48%)  
  SLED 6 (21%) 4 (14%)  
  Peritoneal dialysis 0 (0%) 2 (7%)  
SOFA score, mean (SD) 13.8 (4.4) 13.3 (5.0) 0.71
Type of fluid, n (%)
 Crystalloid 23 (79) 23 (77) 0.81
 Colloid 15 (52) 13 (43) 0.52
Inotrope/vasopressor use, n (%) 25 (86) 25 (83) > 0.99
 Adrenaline 8 (28) 6 (20) 0.49
 Noreadrenaline 20 (69) 22 (73) 0.71
 Dopamine 8 (28) 4 (13) 0.17
 Dobutamine 4 (14) 3 (10) 0.71
 Vasopressin 0 (0) 0 (0) > 0.99
 Terlipressin 1 (3) 0 (0) 0.49
Inotropic score (μg/kg/min), median (Q1, Q3) 36 (7, 70) 30 (2, 83) 0.96
Vasopressor index (μg/kg/min/mmHg), median (Q1, Q3) 0.4 (0.1, 1.1) 0.4 (0.1, 1.1) 0.93
EAA at enrollment, median (Q1, Q3) 0.8 (0.7, 1.0) 0.7 (0.7, 0.9) 0.24
Presepsin (pg/ml), median (Q1, Q3) 5514 (4088, 10,513) 5030 (2459, 10,734) 0.47
  1. Data represent sample size and column percentage unless otherwise noted
  2. PMX-HP polymyxin B hemoperfusion, SD standard deviation, BMI body mass index, Q1 25th percentile, Q3 75th percentile, BUN blood urea nitrogen, AKI acute kidney injury, RRT renal replacement therapy, CRRT continuous renal replacement therapy, SLED sustained low-efficiency dialysis, CVS SOFA cardiovascular Sequential Organ Failure Assessment, EAA endotoxin activity assay
  3. aFisher’s exact test for categorical variables; Student’s t test or Kruskal–Wallis test for continuous variables, Italic data represent P value statistically significant