Table 3 Hemodynamic variables and tissue perfusion markers during 8-h intervention period
Variable | GDHT group (n = 64) | Usual care group (n = 64) | p |
|---|---|---|---|
ΔPCO2 (%) | 0.9 | ||
0 h | 6.8 ± 4.4 | 6.8 ± 4.9 | |
2 h | 7.5 ± 5.8 | 6.9 ± 4.7 | |
8 h | 6.0 ± 3.3 | 6.8 ± 4.2 | |
BE (mmol) | 0.9 | ||
0 h | −3.7 ± 2.9 | −3.7 ± 3.0 | |
2 h | −4.1 ± 3.7 | −3.4 ± 2.9 | |
8 h | −2.4 ± 2.7 | −2.9 ± 3.0 | |
Lactate (mmol/L) | 0.9 | ||
0 h | 2.6 ± 1.5 | 2.8 ± 2.3 | |
2 h | 2.9 ± 2.0 | 3.0 ± 2.3 | |
8 h | 2.9 ± 1.8 | 3.0 ± 2.5 | |
HR (bpm) | 0.9 | ||
0 h | 83.1 ± 21.6 | 85.5 ± 23.9 | |
2 h | 82.9 ± 20.7 | 83.9 ± 22.6 | |
8 h | 88.2 ± 21.3 | 82.9 ± 18.9 | |
MAP (mmHg) | 0.3 | ||
0 h | 94.5 ± 19.6 | 91.6 ± 17.8 | |
2 h | 88.1 ± 15.6 | 87.3 ± 14.7 | |
8 h | 85.3 ± 16.9 | 82.1 ± 15.2 | |
ScvO2 (%) | 0.2 | ||
0 h | 75.7 ± 9.0 | 77.1 ± 9.0 | |
2 h | 75.6 ± 8.7 | 77.4 ± 6.6 | |
8 h | 78.7 ± 6.6 | 76.4 ± 8.0 | |
CI (L/min/m2) | |||
0 h | 2.9 ± 1.0 | – | |
2 h | 2.9 ± 0.9 | – | |
8 h | 3.1 ± 1.0 | – |