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Table 1 Clinical characteristics of the patients included in the investigation

From: TIMP-2/IGFBP7 predicts acute kidney injury in out-of-hospital cardiac arrest survivors

Characteristic Study
population
(n = 48)
Patients
with AKI
(n = 31)
Patients
without AKI
(n = 17)
P value
Age (years) 63 ± 11 63 ± 12 62 ± 9 0.84
Female – n/total n (%) 4/48 (8) 2/31 (7) 2/17 (12) 0.61
Medical history
 Diabetes mellitus – n/total n (%) 8/48 (17) 5/31 (16) 3/17 (18) 1
 Arterial hypertension – n/total n (%) 25/48 (52) 15/31 (48) 10/17 (59) 0.56
 Coronary heart disease – n/total n (%) 42/48 (88) 28/31 (90) 14/17 (82) 0.68
 Advanced renal disease – n/total n (%) 11/48 (23) 7/31 (23) 4/17 (22) 0.42
Cause of cardiac arrest
 Cardiogenic shock 42/48 (87.5) 27/31 (87) 15/17 (88) 1
 Myocardial infarction – n/total n (%) 32/48 (67) 23/31 (74) 9/17 (59) 0.20
  - Primary arrhythmia – n/total n (%) 10/48 (21) 4/31 (13) 6/17 (35) 0.14
 Septic shock 6/48 (12.5) 4/31 (16) 2/17 (12) 1
  - Pulmonary focus – n/total n (%) 5/48 (10) 3/31 (10) 2/17 (12) 1
  - Skin infection – n/total n (%) 1/48 (2) 1/31 (3) 0/17 (0) 1
 Witnessed cardiac arrest – n/total n (%) 33/48 (69) 18/31 (58) 15/17 (88) <0.05
 Basic life support provided by
bystander – n/total n (%)
18/48 (38) 13/31 (42) 5/17 (29) 0.50
 Ventricular fibrillation or pulseless
ventricular tachycardia – n/total n (%)
41/48 (85) 26/31 (84) 15/17 (88) 1
 Number of defibrillations/shocks 3.3 ± 2.5 3.6 ± 2.7 2.8 ± 1.8 0.36
 Dose of epinephrine during CPR (mg) 3.3 ± 3.8 4.5 ± 4.1 1.5 ± 2.0 <0.05
 Time from determined collapse to ROSC (min) 23 ± 19 25 ± 17 14 ± 5 <0.05
Outcome
 Period of ICU hospitalization (days) 17 ± 12 19 ± 9 16 ± 19 0.42
 Ventilation time (days) 10 ± 9 9 ± 6 12 ± 9 0.50
 Hospital mortality – n/total n (%) 14/48 (29) 13/31 (42) 1/17 (6) <0.01
 Favourable neurological outcome – n/total n (%) 29/48 (60) 15/31 (48) 14/17 (82) 0.03
  1. AKI acute kidney injury, CPR cardiopulmonary resuscitation, ROSC return of spontaneous circulation, ICU Intensive Care Unit