Table 1 Clinical characteristics of the patients included in the investigation
From: TIMP-2/IGFBP7 predicts acute kidney injury in out-of-hospital cardiac arrest survivors
Characteristic | Study population (n = 48) | Patients with AKI (n = 31) | Patients without AKI (n = 17) | P value |
|---|---|---|---|---|
Age (years) | 63 ± 11 | 63 ± 12 | 62 ± 9 | 0.84 |
Female – n/total n (%) | 4/48 (8) | 2/31 (7) | 2/17 (12) | 0.61 |
Medical history | ||||
Diabetes mellitus – n/total n (%) | 8/48 (17) | 5/31 (16) | 3/17 (18) | 1 |
Arterial hypertension – n/total n (%) | 25/48 (52) | 15/31 (48) | 10/17 (59) | 0.56 |
Coronary heart disease – n/total n (%) | 42/48 (88) | 28/31 (90) | 14/17 (82) | 0.68 |
Advanced renal disease – n/total n (%) | 11/48 (23) | 7/31 (23) | 4/17 (22) | 0.42 |
Cause of cardiac arrest | ||||
Cardiogenic shock | 42/48 (87.5) | 27/31 (87) | 15/17 (88) | 1 |
Myocardial infarction – n/total n (%) | 32/48 (67) | 23/31 (74) | 9/17 (59) | 0.20 |
- Primary arrhythmia – n/total n (%) | 10/48 (21) | 4/31 (13) | 6/17 (35) | 0.14 |
Septic shock | 6/48 (12.5) | 4/31 (16) | 2/17 (12) | 1 |
- Pulmonary focus – n/total n (%) | 5/48 (10) | 3/31 (10) | 2/17 (12) | 1 |
- Skin infection – n/total n (%) | 1/48 (2) | 1/31 (3) | 0/17 (0) | 1 |
Witnessed cardiac arrest – n/total n (%) | 33/48 (69) | 18/31 (58) | 15/17 (88) | <0.05 |
Basic life support provided by bystander – n/total n (%) | 18/48 (38) | 13/31 (42) | 5/17 (29) | 0.50 |
Ventricular fibrillation or pulseless ventricular tachycardia – n/total n (%) | 41/48 (85) | 26/31 (84) | 15/17 (88) | 1 |
Number of defibrillations/shocks | 3.3 ± 2.5 | 3.6 ± 2.7 | 2.8 ± 1.8 | 0.36 |
Dose of epinephrine during CPR (mg) | 3.3 ± 3.8 | 4.5 ± 4.1 | 1.5 ± 2.0 | <0.05 |
Time from determined collapse to ROSC (min) | 23 ± 19 | 25 ± 17 | 14 ± 5 | <0.05 |
Outcome | ||||
Period of ICU hospitalization (days) | 17 ± 12 | 19 ± 9 | 16 ± 19 | 0.42 |
Ventilation time (days) | 10 ± 9 | 9 ± 6 | 12 ± 9 | 0.50 |
Hospital mortality – n/total n (%) | 14/48 (29) | 13/31 (42) | 1/17 (6) | <0.01 |
Favourable neurological outcome – n/total n (%) | 29/48 (60) | 15/31 (48) | 14/17 (82) | 0.03 |