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Table 5 Sensitivity analysis demonstrating the integrated effect of various admission times and admission conditions on ICU mortality, hospital mortality, and length of stay

From: Association between afterhours admission to the intensive care unit, strained capacity, and mortality: a retrospective cohort study

Outcome

Between 00:00 and 06:59h

Between 00:00 and 06:59 h on non-work day

Between 00:00 and 06:59 h and during October–March

 

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

Mortality

      

 Death in ICU

1.10 (0.98–1.23)

0.10

1.13 (0.96–1.34)

0.14

1.15 (0.99–1.33)

0.060

 Death within 30 h in ICU

1.28 (1.03–1.58)

0.024

1.44 (1.07–1.94)

0.018

1.38 (1.06–1.80)

0.016

 Death within 3 days in ICU

1.17 (0.98–1.39)

0.075

1.34 (1.04–1.72)

0.023

1.37 (1.11–1.70)

0.0039

 Death within 7 days in ICU

1.14 (0.98–1.31)

0.091

1.34 (1.09–1.66)

0.0068

1.23 (1.02–1.49)

0.028

 Death in hospital

1.02 (0.92–1.13)

0.70

1.08 (0.93–1.26)

0.33

1.13 (0.99–1.29)

0.065

Length of stay

      

 LOS in ICU

0.80 (0.66–0.97)

0.026

0.80 (0.67–0.94)

0.0084

0.89 (0.72–1.09)

0.26

 LOS in hospital

1.01 (0.85–1.20)

0.91

0.94 (0.81–1.10)

0.43

0.98 (0.82–1.16)

0.78

 

Between 00:00 and 06:59 h and bed occupancy ≥ 90%

Between 00:00 and 06:59 h and bed occupancy ≥ 95%

Afterhours and clustering admissions per bed ≥ 0.15

 

OR (95% CI)

p value

OR (95% CI)

p value

OR (95% CI)

p value

Mortality

      

 Death in ICU

1.21 (1.03–1.43)

0.019

1.26 (1.01–1.58)

0.039

1.08 (0.97–1.20)

0.15

 Death within 30 h in ICU

1.37 (1.02–1.85)

0.037

1.34 (0.88–2.03)

0.18

1.25 (1.02–1.53)

0.030

 Death within 3 days in ICU

1.33 (1.04–1.69)

0.021

1.26 (0.91–1.76)

0.17

1.18 (1.00–1.38)

0.049

Death within 7 days in ICU

1.25 (1.01–1.54)

0.039

1.24 (0.93–1.66)

0.15

1.16 (1.01–1.33)

0.034

 Death in hospital

1.11 (0.96–1.29)

0.17

1.12 (0.91–1.37)

0.28

1.05 (0.95–1.15)

0.33

Length of stay

 LOS in ICU

0.79 (0.63–0.98)

0.031

0.97 (0.91–1.03)

0.26

0.94 (0.89–1.01)

0.083

 LOS in hospital

1.08 (0.88–1.33)

0.46

1.02 (0.90–1.16)

0.72

0.97 (0.90–1.04)

0.32

  1. OR estimates and their 95% CIs were calculated based on parameter estimates; parameter estimates of integrated effect were based on 1 million times simulation experiments
  2. CI confidence interval, ICU intensive care unit, LOS length of stay, OR odds ratio
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