Table 1 Clinical characteristics and outcomes of the study cohort according to whether or not they received a transfusion during their ICU stay
From: Worldwide audit of blood transfusion practice in critically ill patients
Characteristic | All patients N = 9553 | No transfusion N = 7042 | Transfusion N = 2511 | p value |
|---|---|---|---|---|
Age (years), mean ± SD | 59.9 ± 18.0 | 59.5 ± 18.3 | 60.9 ± 17.3 | 0.002 |
Male, n (%) | 5669 (60.1) | 4180 (60.2) | 1489 (59.8) | 0.736 |
Admission severity scores, mean ± SD | ||||
SAPS II | 41.3 ± 17.7 | 39.7 ± 17.7 | 45.7 ± 17.1 | <0.001 |
SOFA score | 6.4 ± 4.2 | 5.4 ± 3.7 | 8.1 ± 4.3 | <0.001 |
Type of admission, n (%) | <0.001 | |||
Medical | 5089 (56.1) | 4097 (61.2) | 992 (40.9) | |
Surgical | 3317 (36.6) | 2063 (31.0) | 1254 (51.7) | |
Trauma | 607 (6.7) | 436 (6.6) | 171 (6.8) | |
Others | 61 (0.7) | 51 (0.8) | 10 (0.4) | |
Source of admission, n (%) | <0.001 | |||
Ambulance | 3590 (37.6) | 2974 (42.2) | 616 (24.5) | |
Hospital floor | 2512 (26.3) | 1703 (24.2) | 809 (32.2) | |
OR/ER | 1749 (18.3) | 1081 (15.4) | 668 (26.6) | |
Other hospital | 937 (9.8) | 674 (9.6) | 263 (10.5) | |
Others | 765 (8.0) | 610 (8.7) | 155 (6.2) | |
Comorbid conditions | ||||
COPD | 1182 (12.4) | 907 (12.9) | 275 (11.0) | 0.012 |
Diabetes mellitus insulin-dependent | 925 (9.7) | 644 (9.1) | 281 (11.2) | 0.003 |
Chronic heart failure (NYHA III-IV) | 875 (9.2) | 627 (8.9) | 248 (9.9) | 0.147 |
Chronic renal failure | 875 (9.2) | 549 (7.8) | 326 (13.0) | <0.001 |
Non-metastatic cancer | 1011 (10.6) | 659 (9.4) | 352 (14.0) | <0.001 |
Immunosuppression | 727 (7.6) | 459 (6.5) | 268 (10.7) | <0.001 |
Cirrhosis | 334 (3.5) | 183 (2.6) | 151 (6.0) | <0.001 |
Metastatic cancer | 320 (3.3) | 201 (2.9) | 119 (4.7) | <0.001 |
Hematological cancer | 207 (2.2) | 110 (1.6) | 97 (3.9) | <0.001 |
HIV | 69 (0.7) | 46 (0.7) | 23 (0.9) | 0.182 |
Number of comorbidities, n (%) | <0.001 | |||
Any | 5195 (54.4) | 3012 (42.8) | 1346 (53.6) | |
1 | 2667 (27.9) | 1936 (27.5) | 731 (29.1) | |
2 | 1162 (12.2) | 755 (10.7) | 407 (16.2) | |
3 | 403 (4.2) | 245 (3.5) | 158 (6.3) | |
≥ 4 | 126 (1.3) | 76 (1.1) | 50 (2.0) | |
Mortality rates, n (%) | ||||
ICU | 1507 (16.2) | 976 (14.3) | 531 (21.5) | <0.001 |
Hospital | 2006 (22.3) | 1286 (19.6) | 720 (30.0) | <0.001 |
Length of stay, all patients, median (IQR) | ||||
ICU | 3.0 (2.0–6.0) | 3.0 (1.0–5.0) | 5.0 (3.0–11.0) | <0.001 |
Hospital | 10.0 (5.0–20.0) | 8.0 (4.0–16.0) | 15.0 (7.0–30.0) | <0.001 |
Length of stay, survivors, median (IQR) | ||||
ICU | 3.0 (2.0–6.0) | 2.0 (1.0–6.0) | 5.0 (3.0–11.0) | <0.001 |
Hospital | 11.0 (6.0–21.0) | 10.0 (5.0–18.0) | 17.0 (9.0–35.0) | <0.001 |
Length of stay, non-survivors, median (IQR) | ||||
ICU | 3.0 (1.0–8.0) | 2.0 (1.0–6.0) | 7.0 (2.5–15.0) | <0.001 |
Hospital | 5.0 (2.0–13.0) | 4.0 (1.0–9.0) | 9.5 (3.0–20.5) | <0.001 |