Table 1 Demographic data of the included patients
Characteristics | All patients (N = 24) |
|---|---|
Male sex, n (%) | 14 (61) |
Age, years | 53 ± 17 |
Comorbidities, n (%) | |
Arterial hypertension | 3 (13) |
Diabetes mellitus | 5 (21) |
Tobacco use | 2 (10) |
Others | 3 (13) |
Origin of patients, n (%) | |
Emergency room | 12 (50) |
Ward | 5 (21) |
Operating room | 7 (29) |
Source of sepsis, n (%) | |
Lung | 7 (28) |
Urinary | 5 (21) |
Abdominal | 5 (21) |
Other sources | 5 (21) |
Undetermined | 2 (8) |
Hemodynamic data | |
Norepinephrine dosage D0, μg/kg/minute | 0.3 (0.1–0.5) |
Lactate D0, mg/dl | 22 (18–36) |
Mean arterial pressure D0, mmHg | 70 (63–78) |
Ventilatory data | |
Use of mechanical ventilation D0, n (%) | 16 (67) |
Tidal volume D0, ml | 500 ± 88 |
PEEP D0, cmH2O | 8 ± 2.7 |
Fraction of inspired oxygen | 0.4 ± 0.17 |
Peripheral oxygen saturation D0, % | 96 ± 2 |
Duration of mechanical ventilation, days | 3 (2.25–7) |
Hematologic and inflammatory data | |
Leukocytes D0, cells/mm3 | 18,974 ± 9790 |
Leukocytes D7, cells/mm3 | 13,270 ± 6262 |
Hemoglobin D0, g/dl | 10.4 ± 1.6 |
Hemoglobin D7, g/dl | 9.7 ± 1.7 |
Platelets D0, 103 cells/mm3 | 185 ± 134 |
Platelets D7, 103 cells/mm3 | 261 ± 114 |
CRP D0 (n = 18), mg/dl | 290 (212–327) |
CRP D7 (n = 17), mg/dl | 51 (30–125) |
Procalcitonin D0 (n = 9), ng/ml | 15.7 (2–22.4) |
SAPS3 score | 57.7 ± 6.2 |
SOFA score D0 | 8.4 ± 3.3 |
SOFA score D7 | 1.7 ± 3.8 |
ICU length of stay, days | 5 (4–7.75) |
Hospital length of stay, days | 13.5 (8–22.5) |
Hospital mortality, n (%) | 8 (35) |