From: 38th International Symposium on Intensive Care and Emergency Medicine
Characteristics | All patients, (n = 129) * | No fluid overload, (n = 73) | Fluid overload, (n = 47) | p-value |
---|---|---|---|---|
Age, mean (SD), years | 65.69 (11.95) | 66.88 (10.08) | 63.20 (13.45) | 0.091§ |
Male sex, n (%) | 94 (73.4) | 56 (76.7) | 33 (70.2) | 0.562 |
Site of infection, n (%) | Â | Â | Â | Â |
Pneumonia | 94 (75.2) | 55 (78.6) | 32 (69.6) | 0.381 |
Peritonitis | 32 (25.6) | 16 (22.9) | 14 (30.4) | 0.487 |
Daily fluid balance, mean (SD) | Â | Â | Â | Â |
Day 1 | 1,604.44 (2,806.21) | 1,163.82 (1,848.98) | 2,117.77 (3,915.37) | 0.075§ |
Day 2 | 1,618.97 (1,547.52) | 1,142.68 (1,431.51) | 2,387.66 (1,443.90) | <0.001§ |
Day 3 | 1,263.71 (2,955.08) | 608.88 (1,387.50) | 2,475.89 (4,213.05) | 0.001§ |
Day 4 | 459.16 (1,642.37) | 88.68 (1,561.96) | 1,041.81 (1,653.48) | 0.002§ |
Day 5 | 91.20 (1,325.04) | -272.52 (1,184.24) | 691.45 (1,410.06) | <0.001§ |
Cumulative fluid balance from day 1 to day 5 | 5,041.86 (6,789.93) | 2,738.05 (4,217.44) | 8,715.49 (8,619.00) | <0.001§ |
Delta SOFA score between day 1 to day 5 | 3.55 (4.01) | 4.52 (3.74) | 2.15 (3.50) | 0.001§ |
Outcomes | Â | Â | Â | Â |
ICU length of stay | 17.15 (19.06) | 11.71 (10.61) | 27.66 (25.35) | <0.001§ |
28-day mortality, n (%) | 44 (34.1) | 21 (28.8) | 15 (31.9) | 0.870 |
90-day mortality, n (%) | 55 (42.6) | 25 (34.2) | 22 (46.8) | 0.236 |
Ventilator free-days at day 28 | 10.81 (10.59) | 13.84 (10.96) | 7.19 (8.43) | 0.001§ |
Duration of RRT | 4.50 (3.17) | 5.21 (3.18) | 3.85 (2.83) | 0.019§ |
Catecholamine free-days at day 10 | 1.77 (4.47) | 1.47 (4.92) | 2.45 (4.04) | 0.257 |
§ represents p-value considered statistically sign |  |  |  |  |
* Fluid overload status is lacking for 9 patients | Â | Â | Â | Â |